BACKGROUND Nanomaterials have unique advantages in controlling stem cell function due to their biomimetic characteristics and special biological and mechanical properties. Controlling adhesion and differentiation of stem cells is critical for tissue regeneration. METHODS This in vitro study investigated the effects of nano-hydroxyapatite, nano-hydroxyapatite-polylactide- co-glycolide (PLGA) c...

This work describes the hydroxyapatite nanoparticle (HAP) preparation from eggshell waste and their application as an adsorbent for Cephalexin (Ceph) antibiotic removal aqueous solutions. Chemical precipitation with phosphoric acid was used to evaluate feasibility of calcium oxide HAP preparation. The structural properties were characterized by X-ray diffraction, which revealed formation crysta...

A hydrothermal method of synthesizing hydroxyapatite by heating a precipitate, formed by mixing Ca(NO3)2⋅4H2O and (NH4)2HPO4 with distilled water, in a hydrothermal reactor at 200 C for 24-72 hrs is described. A treatment time of 24 hrs produced single phase (as shown by XRD) hydroxyapatite powder, however for longer treatment times XRD patterns were indicative of the presence of a secondary ph...

Bone loss associated with degenerative disease and trauma is a clinical problem increasing with the aging population. Thus, effective bone augmentation strategies are required; however, many have the disadvantages that they require invasive surgery and often the addition of expensive growth factors to induce osteoblast differentiation. Here, we investigated a LaponiteÒ crosslinked, pNIPAM-DMAc ...

This paper reports a high-yield process to fabricate biomimetic hydroxyapatite nano-particles or nano-plates. Hydroxyapatite is obtained by simultaneous dripping of calcium chloride (CaCl2) and ammonium hydrogen phosphate (NH4)2HPO4 solutions into a reaction vessel. Reactions were carried out under various pH and temperature conditions. The morphology and phase composition of the precipitates w...

Injectable bone fillers have emerged as an alternative to the invasive surgery often required to treat bone defects. Current bone fillers may benefit from improvements in dynamic properties such as shear thinning during injection and recovery of material stiffness after placement. Negatively charged inorganic hydroxyapatite (HAp) nanoparticles (NPs) were assembled with positively charged organi...

For many years, glass-polyalkenoate cements have been described as possessing the unique properties of self-adherence to human hard tissues, such as bones or teeth. However, direct experimental evidence to prove the existence of chemical bonding has not been advanced. X-ray Photoelectron Spectroscopy (XPS) was used to analyze the chemical interaction of a synthesized polyalkenoic acid with enam...

Hydroxyapatite nanocrystals in natural form are a major component of bone--a known piezoelectric material. Synthetic hydroxyapatite is widely used in bone grafts and prosthetic pyroelectric coatings as it binds strongly with natural bone. Nanocrystalline synthetic hydroxyapatite films have recently been found to exhibit strong piezoelectricity and pyroelectricity. While a spontaneous polarizati...

In the present paper, nanometer scale hydroxyapatite powders with a rod-like shape, were prepared using combined ultrasonic and microwave heating-based method. Subsequent annealing of as-synthesized at 800 ℃ for 2 h produced nanoparticles rectangular granular morphology. The particles characterized X-ray diffraction Fourier transform infrared spectroscopy methods. Also, nanoparticle ...