Coatings of orthopedic implants are investigated to improve the osteoinductive and osteoconductive properties of the implant surfaces and thus to enhance periimplant bone formation. By applying coatings that mimic the extracellular matrix a favorable environment for osteoblasts, osteoclasts and their progenitor cells is provided to promote early and strong fixation of implants. It is known that...

the purpose of this study was to investigate the deposition of the hydroxyapatite (ha) coating via the electrophoresis procedure. the ha deposition was performed in an ethanol, methanol, acetone and isopropanol suspension. methanol was found to be the best deposition media. among the different environmental conditions, including the encapsulation of the samples under two vacuum types of pressur...

It has been suggested that surface modification with a thin hydroxyapatite (HA) coating enhances the osseointegration of titanium implants. However, there is insufficient information about the biological processes involved in the HA-induced response. This study aimed to investigate the inflammatory cell response to titanium implants with either amorphous or crystalline thin HA. Human mononuclea...

Titanium is widely used as material for permanent implants in orthopedic and dental applications. It is well known that Ti shows a mechanically stable interface towards bone (osseointegration). The good biological properties are due to the beneficial properties of the native oxide (TiO2) that forms on Ti when exposed to oxygen. The native titanium oxide on Ti is usually amorphous and very thin,...

Fabrication of bioactive and mechanical matched bone substitutes is crucial for clinical application in bone defects repair. In this study, nano-hydroxyapatite/polyamide (nHA/PA) composite was coated on injection-moulded PA by a chemical corrosion and phase-inversion technique. The shear strength, gradient composition and pore structure of the bioactive coating were characterized. Osteoblast-li...

a r t i c l e i n f o The structure of an implant's coating can significantly affect its physical and chemical properties, and eventually – its clinical performance. In this paper, the nanostructure of an electrochemically deposited hydroxyapatite (EDHA) coating was studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), and high-resolution transmission electron microscopy (HRTE...

Despite the excellent osseointegration of carbon-fiber-reinforced polyetheretherketone (CFR/PEEK) with a surface hydroxyapatite (HA) coating, the bone-implant interfacial shear strength of HA-coated CFR/PEEK after osseointegration is unclear. We examined the interfacial shear strength of HA-coated CFR/PEEK implants after in vivo implantation in a rabbit femur-implant pull-out test model. HA coa...

In recent years, research on titanium and its alloys had increased significantly for hard tissue replacement and dental applications due to their excellent mechanical properties such as high strength to weight ratio, low density and biocompatibility. However, there are some surface originated problems associated with titanium (Ti): poor implant fixation, lack of osseoconductivity, wear and corr...

PURPOSE To evaluate treatment outcomes of hydroxyapatite-coated implants in comparison to nonhydroxyapatite-coated implants. MATERIALS AND METHODS A comprehensive electronic search was performed through MEDLINE, EMBASE, the Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), the UK National Research Register, and Conference proceedings c...

Novel Ca-Si-Ti-based sphene (CaTiSiO5) ceramics possess excellent chemical stability and cytocompatibility. The aim of this study was to prepare sphene coating on titanium alloy (Ti-6Al-4V) for orthopaedic applications using the plasma spray method. The phase composition, surface and interface microstructure, coating thickness, surface roughness and bonding strength of the plasma-sprayed sphene...