OBJECTIVE Although it has been shown that prophylactic vaccination can induce genital immunity, there is inadequate information on human papillomavirus (HPV) vaccine-induced oral immunity, which is of particular interest due to HPV-associated oropharyngeal malignancies and recurrent respiratory papillomatosis. Therefore, we assessed the efficacy of various HPV vaccines against oral HPV pseudovi...

BACKGROUND Little is known about the origin of methylenedioxymethamphetamine (MDMA, ecstasy). The most commonly repeated statement in the medical literature is that MDMA was synthesized by the German pharmaceutical company Merck in 1912 in order to develop an appetite suppressor. AIM To reconstruct the true story of the first known description of MDMA at Merck using the original documents. ...

Disclosure: Yehuda Chowers has received consulting/lecture fees from AbbVie, Janssen, Takeda, and Protalix. Remo Panaccione is a consultant for AbbVie/Abbott, Amgen, Aptalis, AstraZeneca, Baxter, Bristol-Myers Squibb, Celgene, Cubist, Eisai, Ferring, Gilead, Janssen, Merck, Robarts, Salix, Samsung, Shire, Centocor, Elan, GlaxoSmithKline, UCB, Pfizer, and Takeda; has participated in speaker bure...

the aim of this experiment was to study the effects of hydrochloric and butyric acids addition to broiler diets on performance, carcass characteristics, intestinal microbial population and intestinal histology. two hundred eighty ross 308 one-day old female broiler chicks were assigned to 7 dietary treatments and 4 replicates of 10 chicks in a completely randomized design. experimental treatmen...

Propylamino-functionalized mesoporous thin films were synthesized via co-condensation of the oxide precursor tetraethoxysilane (TEOS, Merck) and the amine precursor 3-aminopropyltriethoxysilane (APTES, Fluka 98%) in the presence of the template (F127 block copolymer, Aldrich, Mw ~13600). The precursor solution was prepared using 0.8 TEOS:0.2 APTES:0.005 F127:24 EtOH:5.2 H2O:0.28 HCl. This solut...

ASCO’s conflict of interest policy, please refer to the Author Disclosure Declaration and the Disclosures of Potential Conflicts of Interest section in Information for Contributors. Employment or Leadership Position: None Consultant or Advisory Role: Alberto F. Sobrero, Bayer (C), Amgen (C), Roche (C), Merck Serono (C), Astra Zeneca (C), sanofi-aventis (C) Stock Ownership: None Honoraria: Alber...

background: histamine is a food-borne chemical hazard which causes scombroid poisoning. the efficiency of histamine recovery from fish is greatly influenced by selection of an appropriate extraction solvent. hence, in this study the efficiency of different extraction solvents on recovery of histamine from fresh, frozen and canned fish was evaluated. methods: fresh, frozen and canned rainbow tro...