in the last decades researchers had focused on developing a vaccine against tick based on protective antigen. recombinant vaccines based on concealed antigen from boophilus microplus have been developed in australia and cuba by the name of tickgard and gavac (de la fuente and kocan, 2006). further studies on this antigen have shown some extent of protection against other species (de vos et al.,...

Hubble Space Telescope images of the core-collapse supernova remnant Cassiopeia A are used to identify highvelocity knots of ejecta located outside the remnant’s main emission shell of expanding debris. These ejecta fragments are found near or ahead of the remnant’s forward shock front and mostly lie from 12000 to 30000 in radial distance from the remnant’s center of expansion. Filter flux rati...

In the interest of optimizing osteogenesis in in vitro, the present study sought to determine how porcine bone marrow stromal cell (BMSc) would respond to different concentrations of hyaluronan (HY) and its different combinations with dexamethasone (Dex) and recombinant human bone morphogenic protein-2 (rhBMP-2). Cellular proliferation was determined by 3H-thymidine incorporation into DNA at bo...

The Chinese herbal formula consisting of Astragalus membranaceus, Epimedium brevicornum, Paeoniae Alba Radix and Radix Ophiopogonis in proper proportions were adopted in order to investigate the immunoenhancing properties of the herbal formula. Fifty ICR mice were randomly divided into 5 groups (NS- NS+Hy-L+Hy-M+Hy-H+Hy ). The mice in hydrocortisone (Hy) groups were injected with hydrocortisone...

The aim of this study was to further characterize the expression and function of human CYP2B6 in a recently generated CYP2A13/ 2B6/2F1-transgenic (TG) mouse model, in which CYP2B6 is expressed selectively in the liver. The inducibility of CYP2B6 by phenobarbital (PB) and dexamethasone (DEX), known inducers of CYP2B6 in human liver, was examined in the TG mice, as well as in TG/Cyp2abfgs-null (o...

1a,25-Dihydroxyvitamin D3 [1,25(OH)2D3] concentrations are regulated by renal CYP27B1 for synthesis and CYP24A1 for degradation. Published plasma and tissue 1,25(OH)2D3 concentrations andmRNA fold change expression of Cyp24a1 andCyp27b1 following repetitive i.p. injections to C57BL/6 mice (2.5 mg 3 kg every 2 days for 4 doses) were fitted with a minimal and full physiologically-based pharmacoki...

The objectives of this study were to determine the diversity, seasonal dynamics and abundance of ticks infesting cattle in Isfahan zone, Iran. The study was conducted in three traditional cattle farms. No acaricides had been applied to cattle at the selected farms. Adult ticks were collected twice per month from different parts of the cattle's body. Environmental data, including relative humidi...

The interrelationship between baroreflex sensitivity expressed in ms/mm Hg (BRS) or in Hz/mm Hg (BRSf), carotid wall thickness (IMT), and age was investigated in hypertensive and normotensive subjects with respect to the mean inter-beat interval (IBI) and blood pressure (BP). BP monitoring was performed in 25 treated hypertensives (Hy; 47.4+/-9.2 years of age) and 23 normotensives (Norm; 44.5+/...

In the title compound, C(18)H(17)NO(4), the hy-droxy-ethanimine group is essentially coplanar with the ring to which it is attached [C-C-N-O torsion angle = 179.94 (14)°]. The mol-ecules are linked into cyclic centrosymmetric R(2) (2)(6) dimers via O-H⋯N hydrogen bonds and the crystal packing is further stabilized by C-H⋯O inter-actions.