helicobacter pylori was the main cause of gastric cancer (gc) in all over the world that results in intestinal- and diffuse-type carcinoma. infection by this bacterium remains chronic for a long time. in vitro studies have highlighted the role of stem cells in gc. h. pylori infection results in tissue injury and the adult/tissue stem cells subsequently start to replace the dead cells. the genet...

previous studies have demonstrated the potential of monotherapy with either mesenchymal stem cells (mscs) or estrogen in autoimmune and cuprizone models of multiple sclerosis (ms). the aim of this study was to examine the effects of co-administration of 17β-estradiol (e2) and adipose-derived mesenchymal stem cells (adscs) on remyelination of corpus callosum axons in a cuprizone model of ms. for...

stem cell based treatments are being increasingly explored for their possible potential to treat various cancers. mesenchymal stem cells believed to possess anti-tumor potential and are preferred for their properties like immune privileged nature, ability to migrate to the site of tumor and capability for multilineage differentiation. this tumor tropism property of mscs could be utilized to del...

background: pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. the aim of this study was to evaluate whether spect/ct myocardial perfusion imaging (mpi) could be used for assessing sheep myocardium following an acute myocardial infarction (mi) and response to int...

background mesenchymal stem cells (mscs) are ideal candidates for treatment of diseases. amniotic membranes are an inexpensive source of mscs (am-msc) without any donor site morbidity in cell therapy. adipose tissue derived stem cells (ascs) are also suitable cells for cell therapy. there is discrepancy in cd271 expression among mscs from different sources. in this study, the characteristics of...

objective: the exfoliated human deciduous tooth (shed) contain multipotent stem cells that identified to be a population of highly proliferative and clonogenic .these cells are capable of differentiating into a variety of cell types including neural cells, adipocytes, and odontoblasts. material and methods: normal exfoliated human deciduous incisors collected from six- to nine-years-old childre...

tissue engineering based on the adipose derived stem cells  promote a strong strategy to propagation of bone, cartilage and fat tissues in the three-dimensional scaffolds, fabricated by combining biological materials with suitable and appropriate growth factors.  in this study, a peo scaffold was used to show that mesenchymal stem cells can attach well; the aim of this study was the investigati...

objective: tooth loss is a common problem and since current tooth replacement methods cannot counter balance with biological tooth structures, regenerating natural tooth structures has become an ideal goal. a challenging problem in tooth regeneration is to find a proper clinically feasible cell to seed.this study was designed to investigate the odontogenic potential of human bone marrow mesench...