human epidermal growth factor receptor 2

Takashi Ishikawa Daisuke Shimizu Takeshi Sasaki Satoshi Morita Mikiko Tanabe Ikuko Ota Kae Kawachi Akinori Nozawa Takashi Chishima Yasushi Ichikawa Itaru Endo Hiroshi Shimada

OBJECTIVE We investigated the pathological effects of neoadjuvant chemotherapy based on the human epidermal growth factor receptor 2 in operable breast cancer. METHODS This prospective clinical study was a pilot involving 63 female patients. Before surgery, patients with tumors overexpressing human epidermal growth factor receptor 2 received four cycles of 60 mg/m(2) anthracycline and 600 mg/...

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Expression of human tyrosine kinase-negative epidermal growth factor receptor amplifies signaling through endogenous murine epidermal growth factor receptor.

Journal: :Journal of Biological Chemistry 1993

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Human epidermal receptor 2-amplified salivary duct carcinoma: Regression with dual human epidermal receptor 2 inhibition and anti-vascular endothelial growth factor combination treatment

Journal: :Head & Neck 2013

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Multidisciplinary Care of a Large Brain Metastasis in a Patient with Hormone-Receptor-Positive Breast Cancer with Ataxia-Telangiectasia Mutation

Journal: :Journal of immunotherapy and precision oncology 2023

ABSTRACT Poly (adenosine diphosphate-ribose) polymerase inhibitors (PARP)i are emerging as standard oncology treatments in various tumor types. The indications will expand PARPi being investigated breast cancer subtypes. Currently, except for BRCA1/2 mutation carriers with human epidermal growth factor receptor 2 (HER2)-negative cancer, there is inadequate identification of predictive biomarker...

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