نتایج جستجو برای: hpv 18

تعداد نتایج: 366353  

2014
Jorge Alberto Gomez Alejandro Lepetic Nadia Demarteau

BACKGROUND In Chile, significant reductions in cervical cancer incidence and mortality have been observed due to implementation of a well-organized screening program. However, it has been suggested that the inclusion of human papillomavirus (HPV) vaccination for young adolescent women may be the best prospect to further reduce the burden of cervical cancer. This cost-effectiveness study compari...

Journal: :iranian journal of virology 0
mostafa mostafavi zadeh isfahan, bozorgmehr street, sadooghi hospital, microbial lab mohammad niakan department of microbiology, shahed university of medical sciences, tehran, iran. reza nedaeinia department of microbiology, deputy of food and drug, isfahan university of medical sciences, isfahan, iran. mostafa manian immunology research centre, iran university of medical science, tehran, iran. amir avan molecular medicine group, department of modern sciences and technologies, school of medicine, mashhad university of medical sciences, mashhad, iran. mozhdeh nedaeinia young researchers and elite club, marvdasht branch, islamic azad university, marvdasht, iran.

abstract background and aims: cervical cancer is among leading causes of cancer related death in women and human papilloma virus (hpv) is one of the important risk factor of this cancer. the aim of the present study was to develop a pcr method for identification of a high carcinogenic type of hpv, hpv 18 using e6 gene as a marker in patients with cervical cancer materials and methods: 92 formal...

2014
Xavier Castellsagué Paulo Naud Song-Nan Chow Cosette M. Wheeler Maria Julieta V. Germar Matti Lehtinen Jorma Paavonen Unnop Jaisamrarn Suzanne M. Garland Jorge Salmerón Dan Apter Henry Kitchener Julio C. Teixeira S. Rachel Skinner Genara Limson Anne Szarewski Barbara Romanowski Fred Y. Aoki Tino F. Schwarz Willy A. J. Poppe F. Xavier Bosch Newton S. de Carvalho Klaus Peters Wiebren A. A. Tjalma Mahboobeh Safaeian Alice Raillard Dominique Descamps Frank Struyf Gary Dubin Dominique Rosillon Laurence Baril

BACKGROUND We examined risk of newly detected human papillomavirus (HPV) infection and cervical abnormalities in relation to HPV type 16/18 antibody levels at enrollment in PATRICIA (Papilloma Trial Against Cancer in Young Adults; NCT00122681). METHODS Using Poisson regression, we compared risk of newly detected infection and cervical abnormalities associated with HPV-16/18 between seronegati...

Journal: :The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2010
Doris M Rivera Medina Alejandra Valencia Alet de Velasquez Li-Min Huang Roman Prymula Jose García-Sicilia Lars Rombo Marie Pierre P David Dominique Descamps Karin Hardt Gary Dubin

PURPOSE Immunization of girls against oncogenic human papillomavirus (HPV) types before sexual debut is important for cervical cancer prevention. This phase III blinded, randomized, controlled trial in adolescent girls assessed safety of the HPV-16/18 AS04-adjuvanted vaccine. METHODS Girls (mean age 12 years) in 12 countries received the HPV-16/18 L1 virus-like particle AS04-adjuvanted vaccin...

Journal: :The Medical journal of Malaysia 2014
B K Lim K Y Ng J Omar S Z Omar B Gunapalaiah Y L Teoh H L Bock D Bi

INTRODUCTION Cervical cancer is the third most common cancer in women worldwide. The HPV-16/18 AS04- adjuvanted vaccine (Cervarix©) has previously been shown to be highly immunogenic with a clinically acceptable safety profile. This phase IIIb, double-blind, randomized (1:1) and placebo controlled trial (NCT00345878) was designed to evaluate the vaccine immunogenicity against HPV-16 and HPV-18 ...

2012
Kyung-Jin Min Kyeong A So Jieun Lee Hye-Ri Hong Jin-Hwa Hong Jae-Kwan Lee Ae-Ree Kim

OBJECTIVE To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. METHODS Besides liquid-based cytology, additional 97 cervical swab samples were collected for HPV genotyping by HPV4A ACE, Cervista HPV assays, and PCR metho...

2014
Dionne N. Dames Elizabeth Blackman Raleigh Butler Emanuela Taioli Stacy Eckstein Karthik Devarajan Andrea Griffith-Bowe Perry Gomez Camille Ragin

BACKGROUND High-risk (HR) HPV genotypes other than 16 and 18 have been detected in a significant proportion of immunocompromised females. We aim to evaluate the frequency of HR HPV genotypes in a population of HIV-positive Caribbean women. METHODS One hundred sixty-seven consecutive, non-pregnant, HIV-positive females ≥18 years were recruited in this study. Each participant received a vaginal...

Journal: :Gynecologic oncology 2008
David Jenkins

Human papilloma virus (HPV)-16 and -18 are responsible for approximately 70% of invasive cervical cancers worldwide. Other oncogenic HPV types account for almost all the remainder. Importantly, HPV-45 and -31 account for approximately 10%. HPV-18 and -45, along with HPV-16, are found in over 90% of endocervical adenocarcinomas. HPV-45 is the third most frequent HPV type in cervical carcinoma an...

Journal: :Genitourinary medicine 1994
H Y Ngan M Stanley S S Liu H K Ma

OBJECTIVE To determine the prevalence of HPV 16 and 18 E6 by DNA detection and p53 abnormal protein expression in cervical cancers in Hong Kong. MATERIALS AND METHODS Seventy-three squamous cell cervical cancer biopsy were analysed. Detection of HPV DNA was carried out by the polymerase chain reaction and Southern blotting (PCR/SB) technique using primers to the HPV16 & 18 E6 region and conse...

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