Recent evidence suggests that natural selection operating on hosts to maintain their microbiome contributes to the emergence of new species, that is, the 'hologenomic basis of speciation'. Here we analyse the gut microbiota of two house mice subspecies, Mus musculus musculus and M. m. domesticus, across their Central European hybrid zone, in addition to hybrids generated in the lab. Hybrid mice...

Using starch-gel electrophoresis and appropriate stain­ ing, four variants have been found in erythrocytes from.the house mouse, Mus muscuius. An allele, designated Es-3 , controlling the presence of a fast-migrating esterase (designated Es-3d) has been found at the Es-3 locus. Tests of substrate specificity, heat sensitivity, and of eserine sulphate and iodoacetamide sensitivity, showed Es-3d ...

One approach to understanding the process of speciation is to characterize the genetic architecture of post-zygotic isolation. As gene regulation requires interactions between loci, negative epistatic interactions between divergent regulatory elements might underlie hybrid incompatibilities and contribute to reproductive isolation. Here, we take advantage of a cross between house mouse subspeci...

House mouse (Mus musculus) is a cosmopolitan pest in agricultural facilities, commodity stores and rural urban environments. It regularly controlled by anticoagulant-based baits. Since the number of registered active ingredients limited, producers are trying to develop new formulations with increased tamper-resistance, attractiveness palatability. Reliable economical methods for laboratory scre...

General parameters of selection, such as the frequency and strength of positive selection in natural populations or the role of introgression, are still insufficiently understood. The house mouse (Mus musculus) is a particularly well-suited model system to approach such questions, since it has a defined history of splits into subspecies and populations and since extensive genome information is ...

House mice (Mus musculus) emit ultrasonic vocalizations (USVs), which are surprisingly complex and have features of bird song, but their functions are not well understood. Previous studies have reported mixed evidence on whether there are sex differences in USV emission, though vocalization rate or other features may depend upon whether potential receivers are of the same or opposite sex. We re...

role in the study of genetics ever since Carl Correns, Hugo De Vries, and Erich Von Tschermak independently rediscovered Mendel’s laws at the beginning of the twentieth century. Because these three scientists, as well as Mendel himself, performed their research entirely on plants, many in the scientific community questioned whether Mendel’s laws could explain the basis for inheritance in animal...

We compared nucleotide sequences of the transcription-initiation region of five mouse ribosomal DNA (rDNA) clones. Two clones were isolated from Japanese wild mice, Mus musculus molossinus, and the other three from BALB/c mice originating in M. m. domesticus. Two BALB/c clones that are derived from the same chromosome are very similar, suggesting the occurrence of intrachromosomal homogenizatio...

Behavioural isolation may lead to complete speciation when partial postzygotic isolation acts in the presence of divergent-specific mate-recognition systems. These conditions exist where Mus musculus musculus and M. m. domesticus come into contact and hybridize. We studied two mate-recognition signal systems, based on urinary and salivary proteins, across a Central European portion of the mouse...