conclusion in breast cancer after nac, the lesion t2 relaxation time was reduced in the responders, and this finding is potentially useful to assess the response to nac. results in 26 cases with nac, the mean lesion t2 relaxation time before nac was 81.34 ± 13.68 ms, compared with 64.50 ± 8.71 ms after nac. significant differences in the lesion t2 relaxation times existed between the pre- and p...

Sensitive profile searches and fold recognition were used to predict the structures of two yeast RNase P/MRP proteins. Rpp1p, which is one of the subunits common to eukaryotes and archaea, is predicted to adopt the seven-stranded TIM-barrel fold found in PHP phosphoesterases. Pop3p, initially thought to be one of the RNase P/MRP subunits unique to yeast, has been assigned the L7Ae/L30e fold. Th...

OBJECTIVE There are only sporadic reports of delayed sino-nasal complications associated with nasopharyngeal carcinoma (NPC) treated with radiotherapy. These include choanal stenosis, osteoradionecrosis, chronic sinusitis, and intranasal synechiae. Most likely, these complications are underestimated as in many institutions nasal endoscopies in NPC patients are not performed routinely. The aim o...

The tendency for experimental and industrial variables to include a certain proportion of outliers has become a rule rather than an exception. These clusters of outliers, if left undetected, have the capability to distort the mean and the covariance matrix of the Hotelling's T2 multivariate control charts constructed to monitor individual quality characteristics. The effect of this distortion i...

CCC-r chart extended approach of CCC charts, is a technique applied when nonconforming items are rarely observed. However, it is usually assumed that the inspection process is perfect in the implementation control charts imperfect inspections may have a significant impact on the performance of the control chart and setting the control limits. This paper first investigates the ...

RNase P preparations from Escherichia coli can be separated into RNA and protein by chromatography, in buffers containing 7 M urea, on Sephadex G-200, DEAE-Sephadex, or CM-Sephadex columns. Neither RNA nor protein components alone exhibits any RNase activity. RNase P activity can be reconstituted by mixing separated RNA and protein components in buffer containing 7M urea followed by dialysis of...

Independently folded domains in RNAs frequently adopt identical tertiary structures regardless of whether they are in isolation or are part of larger RNA molecules. This is exemplified by the P15 domain in the RNA subunit (RPR) of the universally conserved endoribonuclease P, which is involved in the processing of tRNA precursors. One of its domains, encompassing the P15 loop, binds to the 3'-e...