نتایج جستجو برای: homeodomain proteins

تعداد نتایج: 558034  

Journal: :Journal of Phycology 2021

The haploid-diploid life cycle of the filamentous brown alga Ectocarpus involves alternation between two independent and morphologically distinct multicellular generations, sporophyte gametophyte. Deployment developmental program requires TALE homeodomain transcription factors OUROBOROS SAMSARA. In addition, generation has been shown to secrete a diffusible factor that can induce uni-spores swi...

Journal: :The Journal of biological chemistry 2006
Mohammad Q Hassan Rahul S Tare Suk Hee Lee Matthew Mandeville Maria I Morasso Amjad Javed Andre J van Wijnen Janet L Stein Gary S Stein Jane B Lian

Several homeodomain (HD) proteins are critical for skeletal patterning and respond directly to BMP2 as an early step in bone formation. RUNX2, the earliest transcription factor proven essential for commitment to osteoblastogenesis, is also expressed in response to BMP2. However, there is a gap in our knowledge of the regulatory cascade from BMP2 signaling to the onset of osteogenesis. Here we s...

2000
REBECCA A. FILLMORE WARREN E. ZIMMER

Combining reverse transcriptase-polymerase chain reaction (RTPCR) and molecular cloning technologies, we have investigated the expression of homeodomain proteins in chicken gizzard tissues undergoing differentiation. We demonstrate that homeodomain encoding transcripts are found in developing chicken gizzard. An RT-PCR generated 117 bp homeodomain DNA probe was used to screen a gizzard library ...

Journal: :Proceedings of the National Academy of Sciences 1992

Journal: :Cell 2000
James Briscoe Alessandra Pierani Thomas M Jessell Johan Ericson

Distinct classes of neurons are generated at defined positions in the ventral neural tube in response to a gradient of Sonic Hedgehog (Shh) activity. A set of homeodomain transcription factors expressed by neural progenitors act as intermediaries in Shh-dependent neural patterning. These homeodomain factors fall into two classes: class I proteins are repressed by Shh and class II proteins requi...

2010
Stefanie D. Hueber Georg F. Weiller Michael A. Djordjevic Tancred Frickey

The family of Hox-proteins has been a major focus of research for over 30 years. Hox-proteins are crucial to the correct development of bilateral organisms, however, some uncertainty remains as to which Hox-proteins are functionally equivalent across different species. Initial classification of Hox-proteins was based on phylogenetic analysis of the 60 amino acid homeodomain. This approach was s...

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