Background and objectives: Adipose tissue is responsible for releasing various adipokines which have been related to insulin resistance. Understanding the relationship of these adipokines to insulin resistance may help in early diagnosis and faster the development of new treatments for diabetes. The objective of this study was to determine the possible association between these adipokines (visf...

Background: Polyunsaturated fatty acids (PUFA) are found in nuts and seeds, salad dressings and vegetable oil and are prone to oxidation during storage and food preparation. Evidence supports that consumption of oxidized lipids promotes atherosclerosis and glucose intolerance in animal models. However there is a dearth of evidence with regard to the amount of oxidized lipids consumed and its as...

Aims: Insulin resistance is consistence feature in type 2 diabetes mellitus (DM). Several studies demonstrated that serum adenosine deaminase activity (ADA) is elevated in type 2 DM patients. The present study was conducted to estimate serum ADA activity in newly diagnosed type 2 DM patients, compared with control groups and to find out correlation of insulin resistance with serum ADA activity....

Adipokine dysregulation and subclinical inflammation are putative diabetogenic features of adiposity. However, while alterations in adipokines/inflammatory proteins can predict incident type 2 diabetes in longitudinal studies (1–3), evidence for causality is generally hindered by two limitations. First, there is a relative paucity of human data linking changes in adipokines/inflammatory protein...

K im et al. (1) conducted a 2.6-year follow-up study targeting 5,178 inhabitants aged 40 to 70 years to elucidate the effect of serum adiponectin on the risk of development of metabolic syndrome (MetS). The number of participants in the first follow-up survey was 3,862, and the final sample size became 2,044 (831 men and 1,213 women), after exclusion of subjects for several reasons, including l...

Corresponding author: Hye Soon Kim https://orcid.org/0000-0001-6298-3506 Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 41931, Korea E-mail: [email protected] Adipose tissue is currently known as an endocrine organ that secretes a large number of factors termed adipocytokine with diverse actions ...

glucose (M = 95, SD = 9.6), insulin (M = 11.9, SD = 9.8), HOMA-IR (M = 2.9, SD = 2.6), and HbA 1c (M = 5.7, SD = 3.6). All continuous predictor variables were mean-centered and outliers were top-coded. Glucose, insulin, and HOMA-IR were log-transformed to achieve normal distributions. Bivariate correlations showed that BMI was positively associated with all markers of glucose metabolism (r valu...

We read with interest the letter by Mohn et al. regarding the long-term follow-up of β-cell function in 32 children and adolescents previously treated with chemotherapy, but not cranial radiotherapy, for acute lymphoblastic leukaemia. Oral glucose tolerance test performed during 3 follow-up visits showed a progressive reduction of impaired glucose tolerance, as well as an improvement of insulin...

Background/Aims: It is important to establish the association between insulin resistance and renal function; however, the reported associations differ across studies. Different underlying pathophysiologies of the studied populations may affect the associations. There have been no reports on the relationship between insulin resistance and renal function in the presence of hypertension (HT). We i...