نتایج جستجو برای: holo

تعداد نتایج: 1156  

2017
Sven Warhaut Klara Rebecca Mertinkus Philipp Höllthaler Boris Fürtig Mike Heilemann Martin Hengesbach Harald Schwalbe

The full-length translation-regulating add adenine riboswitch (Asw) from Vibrio vulnificus has a more complex conformational space than its isolated aptamer domain. In addition to the predicted apo (apoA) and holo conformation that feature the conserved three-way junctional purine riboswitch aptamer, it adopts a second apo (apoB) conformation with a fundamentally different secondary structure. ...

2017
Peiqiang Li Lijuan Huang Yufang Zheng Xuedong Pan Rui Peng Yueming Jiang Richard H. Finnell Haijie Li Bin Qiao Hong-Yan Wang

Deregulation of folate and vitamin B12 (VB12) metabolism contributes to the risk of congenital heart defects (CHDs). Transcobalamin (TCN2) is essential for transporting VB12 from blood to cells as TCN2-bound VB12 (holo-TC) is the only form for somatic cellular uptake. In this study, we performed an association study between common polymorphisms in 46 one carbon metabolism genes and CHD in 412 C...

Journal: :Journal of large-scale research facilities JLSRF 2016

Journal: :Cancer research 1992
R Hoermann A L Gerbes G Spoettl D Jüngst K Mann

Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ascites of patients with nontrophoblastic malignant tumors and, for comparison, in ascites caused by cirrhotic liver disease. Total hCG immunorea...

Journal: :Proceedings of the National Academy of Sciences 2014

Journal: :Allergo journal international 2021

Summary Iron deficiency is associated with atopy. during pregnancy increases the risk of atopic diseases in children, while both allergic children and adults are more likely to have iron anemia. Immunologically, leads activation antigen-presenting cells, promotion Th2 cells enables antibody class switch B cells. In addition, primes mast for degranulation, an increase their content inhibits degr...

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