Traumatic intracerebral haematomas are a common neurosurgical emergency. Their management, particularly the role of surgical removal, is controversial. Deterioration often occurs late, and is unpredictable. Eight patients with traumatic intracerebral haematomas were admitted to the neurosurgical unit to monitor their clinical state. All were studied within 48 hours of admission with single phot...

The objective was to compare two neurophysiological variables in active amateur boxers with non-boxing sportsmen. 41 boxers and 27 controls were given psychometric tests: 34 boxers and 34 controls underwent technetium-99m hexamethylpropyleneamineoxime single photon emission computerised tomography (Tc-99m HMPAO SPECT) cerebral perfusion scans. The controls performed better at most aspects of th...

Tumor perfusion and oxygenation status have been suggested as factors which may influence treatment outcome in cancer patients. Nuclear medicine assays of tumor perfusion [99mTc-hexamethylpropylenamine oxime (HMPAO)] and tumor hypoxia [123I-iodoazomycin arabinoside (IAZA)] have recently been developed and described. We report on measurements of perfusion and oxygenation status of 27 tumors in 2...

AIM The aim of this study was to assess the role of labelled leukocyte scintigraphy in the diagnosis and monitorization of response to therapy of patients with active bronchiectasis. MATERIAL AND METHODS Twenty patients underwent (99m)Technetium hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) labelled white blood cell (WBC) scintigraphy. A second scintigraphy was performed in 13 patients at 10...

UNLABELLED The aim of this study was to evaluate the diagnostic value, in suspected infectious prostheses, of (99m)Tc-labeled hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) leukocyte scintigraphy interpreted with the addition of a semiquantitative analysis. METHODS By means of a retrospective review, we included a group of 78 consecutive patients with suspected hip or knee prosthesis infectio...

Objectives Brain perfusion SPECT has been widely used for evaluation of brain perfusion and metabolic status. We aimed to compare different quantitative methods on Tc-99m-HMPAO SPET based on visual evaluation. Materials and Methods: Forty-seven patients were enrolled in this comparative study. Tc-99m-HMPAO brain SPET was performed. For semiquantitative analysis, two orbitomeatal (OM) composite ...

OBJECTIVES To study the ability of technetium-99m hexamethyl propylene amineoxime (HMPAO) labelled lymphocyte scintigraphy to quantify synovial inflammation, and to analyse the kinetics of lymphocyte retention in the joints of patients with rheumatoid arthritis (RA). METHODS After isolation of the lymphocytes, the cells were radiolabelled in vitro with 250 MBq 99mTc-HMPAO. The scans were perf...

Objective: The purpose of this study was to investigate if an octadecyl (18C) minicolumn could be applied successfully for quality control of 99mTc exametazime (HMPAO). Methods: The 18C column system using saline eluent was validated against the Whatman 17 method in calculating the percent radiochemical purity of 99mTc-HMPAO. The behavior of 99mTc-pertechnetate (TcO4) and hydrolyzed-reduced 99m...

A simple, rapid and sensitive spectrophotometric method is herewith proposed for the determination of copper(II) by using diamine-dioxime ligand, meso-3,6,6,9-tetramethyl-4,8-diazaundecane-2,10-dione dioxime or meso-HexaMethyl Propylene Amine Oxime (meso-HMPAO). This method is based on the formation of a stable 1 : 1 red-pink complex between copper(II) and meso-HMPAO in aqueous solution. Absorp...