BACKGROUND Home management of malaria (HMM), promoting presumptive treatment of febrile children in the community, is advocated to improve prompt appropriate treatment of malaria in Africa. The cost-effectiveness of HMM is likely to vary widely in different settings and with the antimalarial drugs used. However, no data on the cost-effectiveness of HMM programmes are available. METHODS/PRINCI...

Identification of protein domains is a key step for understanding protein function. Hidden Markov Models (HMMs) have proved to be a powerful tool for this task. The Pfam database notably provides a large collection of HMMs which are widely used for the annotation of proteins in sequenced organisms. This is done via sequence/HMM comparisons. However, this approach may lack sensitivity when searc...

We present a comparison of 6 methods for classification of sports audio. For the feature extraction we have two choices: MPEG-7 audio features and Mel-scale Frequency Cepstrum Coefficients (MFCC). For the classificaiton we also have two choices: Maximum Likelihood Hidden Markov Models (ML-HMM) and Entropic Prior HMM(EP-HMM). EP-HMM, in turn, have two variations: with and without trimming of the...