نتایج جستجو برای: hiv drug
تعداد نتایج: 772533 فیلتر نتایج به سال:
previously, we reported that the kaempferol and kaempferol-7- o -glucoside isolated from securigera securidaca showed potent anti-hsv activity. in the present study the anti-hiv-1 activities of kaempferol and kaempferol-7- o -glucoside are investigated at different concentrations (100, 50, 25 and 10 µg/ml) using hiv-1 p24 antigen kit. real-time polymerase chain reaction (rt-pcr) assay was also ...
conclusions we found a large impact due to nsps for reducing the occurance of hiv among active drug injectors who have been provided sufficient needles and syringes. the coverage of nsps needs to be increased to observe such significant impact. results given the output of the model, we found that among the pwid with sufficient coverage of nsps the hiv rate is 1.02%, while those with insufficien...
objective: to estimate the size of groups at high risk of hiv, network scale up (nsu), an indirect method, was used. methods: 500 kermanian male aged 18 to 45 were recruited. 8 groups at high risk of hiv were defined: users of opium, unknown drug, ecstasy, and alcohol; intra‑venous drug users (idus; males who have extra‑marital sex with females (msf); male who have sex with female sex workers (...
BACKGROUND After rapid scaling up of antiretroviral therapy in HIV-1-infected patients, the data of primary HIV-1 drug resistance in Thailand is still limited. This study aims to determine the prevalence and associated factors of primary HIV-1 drug resistance in Thailand. METHODS A prospective observational study was conducted among antiretroviral-naïve HIV-1-infected Thai patients from 2007 ...
Background:In some countries, one of the first and most common manifestations of HIV positive patients is tuberculosis (TB). HIV positive people are prone to other infections such as tuberculosis due to immune deficiency and reduced CD4+ cell count. Although increasing access to antiretroviral therapy has led to a reduction in HIV-related opportunistic infections and mortality, the simultaneous...
OBJECTIVE HIV infection and illicit drug use are each associated with diminished cognitive performance. This study examined the separate and interactive effects of HIV and recent illicit drug use on verbal memory, processing speed, and executive function in the multicenter Women's Interagency HIV Study. METHODS Participants included 952 HIV-infected and 443 HIV-uninfected women (mean age = 42...
INTRODUCTION Papua New Guinea is a Pacific Island nation of 7.3 million people with an estimated HIV prevalence of 0.8%. ART initiation and monitoring are guided by clinical staging and CD4 cell counts, when available. Little is known about levels of transmitted HIV drug resistance in recently infected individuals in Papua New Guinea. METHODS Surveillance of transmitted HIV drug resistance in...
Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease pertained to the human immune system. Given its crucial role in viral replication, HIV-1 protease (HIV-1 PR) is a prime therapeutic target in AIDS therapy. In this regard, the dynamic aspects of ligand-enzyme interactions may indicate an important role of conformational variability in HIV-1 PR in...
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