background: heroin as opium is being used in two pure and impure forms with known disastrous effects on different body organs including genital system. the aim of this study was to determine the changes in testosterone secretion, the percentage of fertility, changes of the body and testis weight, and gonado somatic index in mice (ballb/c). materials and methods: a total of 90 adult male and fem...

Background: Busulfan is a chemotherapy drug that is widely used for cancer treatment. However, administration of busulfan to male patients with malignant diseases may cause temporary or permanent sterility. Therefore, research into drugs or Materials to reduce the side effects of busulfan on the male reproductive system is necessary. In the present study the protective effects of L-carnitine an...

An experiment was conducted to study the effects of enzyme and phytogenic product (thymol+carvacrol) on the ileal microbial population and jejuna and ileal histomorphology of broilers fed wheat based diet. The experiment was conducted as a 2 × 3 factorial arrangement with 2 levels of enzyme endofeed W (0 and 0.05%) and 3 levels of next enhance 150® (0, 100 and 200 mg/kg). Each of the 6 dietary ...

A 3 × 2 factorial experiment was conducted to investigate the effect of thymol + carvacrol (0, 100 and 200 mg/kg) on ileal microbial population and jejuna and ileal histomorphology of broilers fed Carboxy Methyl Cellulose (CMC: 0 and 2%) containing diet. Each of the 6 dietary treatments was replicated 5 times with 12 chicks each from 0 to 42 days of age. There was no interaction effect of CMC a...

Cadmium (Cd) is one of the most toxic environmental heavy metals to organisms. The prominent toxic effects of Cd on reproductive organs are very well known. Gonad histopathology is a valuable tool for the assessment of endocrine disruption compounds EDCs effects on fish. The aim of this study was to evaluate the reproductive toxicity of cadmium chloride (CdCl2) on histopathology of Zebrafish (D...

Swerdlow et al studied a cohort of 1075 men who had been treated for cryptorchidism. In 120 testes that had been biopsied at the time of orchiopexy the relative risk of subsequent development of testicular cancer was 66.7. The corresponding relative risk in 1285 undescended testes that had also been operated on but not biopsied was 6.7. The estimate for testes that were not biopsied is about as...

background: acyclovir (acv), a synthetic purine nucleoside analogue, is known to be toxic to gonads. objective: the current study evaluated cytotoxicity of acv on histopathological changes in testis tissue and serum testosterone and lipid peroxidation concentrations of male rats. materials and methods: animals were divided into five groups. one group served as control and one group served as co...

A 39-year-old female presented with a fleshy nasal polyp occluding the left nasal cavity, associated with haemopurulent discharge. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scans of the paranasal cavities revealed a large polypoid tumour arising from the left middle turbinate and obstructing the left maxillary sinus ostium. However, no bony or intracranial involvement was id...

AIMS Genotyping is a prerequisite for tyrosine kinase inhibitor therapy in high risk and malignant GIST. About 10% of GISTs are wild-type for KIT but carry PDGFRA mutations. Applying the traditional approach, mutation analysis of these cases is associated with higher costs if all hotspots regions in KIT (exon 9, 11, 13, 17) are performed at first. Our aim was to evaluate the predictive value of...