STUDY OBJECTIVE To establish a histologic diagnosis of pneumonia by consensus of a panel of pathologists, to test the interobserver and intraobserver variation in the histologic diagnosis of pneumonia, to compare the diagnostic accuracy of diagnosing pneumonia with and without preselected histologic criteria, and to establish more specific histologic criteria for the diagnosis of pneumonia. M...

To evaluate efficacy and safety of budesonide oral suspension (BOS) in pediatric patients with eosinophilic esophagitis (EoE). We used pooled data from two 12-week, randomized, double-blind, placebo-controlled trials BOS 2.0 mg b.i.d. (phase 2 [MPI 101-06/NCT01642212] phase 3 [ORBIT1/SHP621-301/NCT02605837]) aged 11–17 years EoE dysphagia. Peak eosinophil counts, the Dysphagia Symptom Questionn...

BACKGROUND AND PURPOSE Plaque morphologic features have been suggested as a complement to luminal narrowing measurements for assessing the risk of stroke associated with carotid atherosclerotic disease, giving rise to the concept of "vulnerable plaque." The purpose of this study was to evaluate the ability of multidetector-row CT angiography (CTA) to assess the composition and characteristics o...

PURPOSE To correlate the results of histopathologic subtyping and grading of lung adenocarcinoma with maximum standardized uptake values (SUVmax) on positron emission tomography (PET)/computed tomography and apparent diffusion coefficient (ADC) values on diffusion-weighted MRI (DWI). MATERIALS AND METHODS Forty-three patients were included. The SUVmax and mean ADC values of tumors were measur...

BACKGROUND Canine cutaneous mast cell tumor (MCT) is a common neoplastic disease associated with a variable biologic behavior. Surgery remains the primary treatment for canine MCT; however, radiation therapy (RT) and chemotherapy are commonly used to treat aggressive MCT. The goals of this study were to evaluate the prognostic utility of histologic grade, c-KIT mutations, KIT staining patterns,...

The concentration of serum IgD was measured in 100 patients with Hodgkin disease; 65 had 3--50-fold increases in IgD levels. Several parameters were found to influence serum IgD concentration: IgD level in older patients (greater than 50 yr) was significantly lower than in the younger patients (P less than 18 yr). IgD concentration was significantly higher in splenectomized than in nonsplenecto...

PURPOSE The presence of retinal nerve fiber layer (RNFL) split bundles recently was described in normal eyes scanned using scanning laser polarimetry. In this study, the authors set out to ascertain whether RNFL split bundles can be found in histologic sections of normal human eyes. DESIGN Histologic study of postmortem human eyes. PARTICIPANTS Fourteen normal postmortem eyes obtained from ...

OBJECTIVE This study aimed to reveal the relationships between histologic grade and other clinicopathologic parameters including intrinsic subtype in Taiwanese women with breast cancer. METHODS There were 1302 women diagnosed with breast cancer recruited for this study. Histologic grade was scored according to the Nottingham-modified Bloom-Richardson grading system. RESULTS Higher tumor gra...

we have studied the patients who had a neck mass on presentation in five medical centers of tehran univ. of medical sciences (infectious disease department, ent department, dentistry faculty, cancer institute) during a period of 14 months. sixty patients, 20 women and 40 men, were eligible for our study. all patients underwent clinical and paraclinical work up and finally had histologic diagnos...