نتایج جستجو برای: histaminergic system
تعداد نتایج: 2231476 فیلتر نتایج به سال:
The human histaminergic system contains approximately 64.000 neurons located in a posterior region of the hypothalamus, the tuberomamillary nucleus. Projections of such a relatively small number of neurons are surprisingly widespread throughout the central nervous system. Histaminergic neurons are highly active during wakefulness and contribute to the physiology of arousal state, exploration, p...
Perinatal asphyxia (PA) is associated with long-term neuronal damage and cognitive deficits in adulthood, such as learning and memory disabilities. After PA, specific brain regions are compromised, including neocortex, hippocampus, basal ganglia, and ascending neuromodulatory pathways, such as dopamine system, explaining some of the cognitive disabilities. We hypothesize that other neuromodulat...
Possible central serotonergic and histaminergic modulation of acute peripheral inflammation was investigated in rats, adopting the formaldehyde-induced acute pedal inflammation as an experimental model. Intracerebroventricular (icv) administration of central inhibitory neurotransmitter, serotonin and its precursor, 5-hydroxytryptophan (5-HTP) attenuated the oedema volume and exudate protein con...
This study was conducted to investigate the possible involvement of the histaminergic system in themediation of ghrelin-induced feeding behavior in broiler chickens. In the trial 1, the effect ofintracerebroventricular (ICV) injection of ghrelin on feed intake was examined in 3-h feed-deprived broilerchickens. In the trials 2 and 3, the chickens were received ICV chlorpheniramine (an H1 recepto...
Prostaglandin E2Activates the Histaminergic System via the EP4Receptor to Induce Wakefulness in Rats
The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing, indicating that ACh activity is critical during early stages of memory processing. During novel taste presentation, there is an increase in AC...
The role of endogenous histamine and H1, H2 and H3 central receptors on food intake in broiler chickenswas investigated. For this purpose, a probe was used to manipulate the concentration of endogenoushistamine by intracerebroventricular (ICV) injection of thioperamide, an H3 receptor antagonist, and R-α-methylhistamine, an H3 receptor agonist and subsequently the effects of brain histaminergic...
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