نتایج جستجو برای: hippocampal ca1 area
تعداد نتایج: 627388 فیلتر نتایج به سال:
Gamma frequency (30-80 Hz) oscillations are implicated in memory processing. Such rhythmic activity can be generated intrinsically in the CA3 region of the hippocampus from where it can propagate to the CA1 area. To uncover the synaptic mechanisms underlying the intrahippocampal spread of gamma oscillations, we recorded local field potentials, as well as action potentials and synaptic currents ...
Reversible inactivation of the medial septal area results in a spatial memory impairment and selective disruption of hilar/CA3, but not CA1, location-specific discharge. The present study examined the possibility that such septal deafferentation produces effects on hippocampal function by altering physiological properties of the primary input and output structures for hippocampus, the entorhina...
We investigated the spatio-temporal dynamics of learning-induced cAMP response element-binding protein activation/phosphorylation (pCREB) in mice trained in a spatial reference memory task in the water maze. Using immunohistochemistry, we examined pCREB immunoreactivity (pCREB-ir) in hippocampal CA1 and CA3 and related brain structures. During the course of spatial learning over Days 1-9, pCREB...
Background & Aims: Due to the fact that nanoscale zinc oxide nanoparticles can pass through the blood brain barrier and have devastating effects on various posts of nervous system, the present study investigated the effects of N-Acetyl cysteine on memory retrieval, hippocampal CA1 pyramidal neurons and some blood serum oxidative stress factors on male Wistar rats treated with zinc oxide nanopar...
Alterations of functional properties of hippocampal networks following repetitive closed-head injury
Traumatic brain injury (TBI) is the leading cause of death for persons under the age of 45. Military service members who have served on multiple combat deployments and contact-sport athletes are at particular risk of sustaining repetitive TBI (rTBI). Cognitive and behavioral deficits resulting from rTBI are well documented. Optimal associative LTP, occurring in the CA1 hippocampal Schaffer coll...
Background: Facing environmental factors during early postnatal life, directly or indirectly via mother-infant relationships, profoundly affects the structure and function of the mammals’ Central Nervous System (CNS). Objectives: This study aimed to evaluate the effect of morphine consumption during the lactation period on short-term synaptic plasticity of the hippocampal Cornu Ammonis 1 (C...
Fear memories guide adaptive behavior in contexts associated with aversive events. The hippocampus forms a neural representation of the context that predicts aversive events. Representations of context incorporate multisensory features of the environment, but must somehow exclude sensory features of the aversive event itself. We investigated this selectivity using cell type-specific imaging and...
Anterograde tracer injections in the middle sector of CA1 in macaque monkeys demonstrate a direct projection to the fundus of the anterior superior temporal sulcus, in area IPa. Terminations are predominantly in layer 3. With regard to both terminal and arbor configuration, these hippocampal-cortical connections are morphologically similar to corticocortical connections to temporal association ...
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