PATRICIA A. BARFORD, JOHN A. BLAIR and FREDERICK J. STAFF Department of Chemistry, University of Aston in Birmingham, Gosta Greem, Birmingham B4 7ET, U.K. It has been frequently claimed that polyglutamate forms of folates are found in animals (Noronha & Silverman, 1962; Shin et al., 1972; Brown et al., 1974) on the basis of column chromatography of these folates and chromatography of 'authentic...

The relative importance of competing pathways for the formation of high-molecular-weight peroxides in the ozonolysis of organic aerosol particles M. Mochida, Y. Katrib, J. T. Jayne, D. R. Worsnop, and S. T. Martin Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA Institute of Low Temperature Science, Hokkaido University, Sapporo, 060-0819, Japan Aerodyne...

PURPOSE The antivascular endothelial growth factor agents ranibizumab and bevacizumab are used to treat ocular neovascular diseases. There have been recent reports of sustained elevation of intraocular pressure after use of either agent, which we hypothesize could be because of high-molecular-weight aggregates. METHODS Enzyme-linked immunosorbent assay, size exclusion chromatography, and poly...

Oral anticoagulation with a vitamin K-antagonist requires special consideration when surgery or interventional procedures are planned. This is mainly due to the half life of vitamin K-antagonists and to the need for safe and effective anticoagulation prior to and during surgery as well as in the postoperative period. So far, the continuous infusion of unfractionated heparin (UFH) has been the m...

genotypes of iranian zel sheep for calpastatin(cast) locus were determined by polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) and polymerase chain reaction-single strand conformation polymorphism (pcr-sscp) methods and for calpain(capn) locus by pcr-sscp. blood samples were collected from 200 purebred zel sheep of zel breeding station located in golestan province i...

in this research, the microstructural of low molecular weight 1,2-polybutadiene (1,2-pbd) was conducted by 1h and 13c nuclear magnetic resonance spectroscopy (nmr) to determine the isomeric contents of 1,4-cis, 1,4-trans and 1,2-vinyl in 1,2-pbd polymer structures. number average molecular weight for low molecular weight 1,2-pbd was measured by nmr techniques and the results were compared with ...

Kinins are vasoactive peptides released from precursors called kininogens, and serum levels of both T- and K-kininogens increase dramatically as rats age. Kinin release is tightly regulated, and here we show that serum kinin levels also increase with age, from 63 +/- 16 nmol/L in young Fisher 344 rats to 398 +/- 102 nmol/L in old animals. Both K- and T-kininogens contribute sequentially to this...

Implantable contraceptive is likely to be a promising new option for fertility control, as we have entered the twenty-first century and the world’s population grows by one billion people in a single decade. The main objective of this study was to develop a subdermal implant for levonorgestrol (a synthetic progestin from 19-norandrostanes) using a high molecular weight biodegradable polymer , i....