This study presents the results of EGSnrc Monte Carlo calculations of the dose distribution surrounding a high dose rate Yb brachytherapy source and 14 high dose rate and pulsed dose rate Ir brachytherapy sources. Energy-weighted spectra of emitted photons, a full set of TG-43 dosimetry parameters, along-away dose tables, and a description of the materials and geometry used for each source are ...

High dose rate brachytherapy (HDR) using 192Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR 192Ir brac...

Pediatric soft-tissue sarcomas are managed with a multimodality treatment program that includes surgery, chemotherapy, and external-beam radiotherapy (teletherapy). The use of teletherapy in young children can result in significant long-term toxicities (especially growth retardation of bones and organs). Brachytherapy, if feasible, is an attractive alternative for the treatment of pediatric sof...

Background: The effectiveness and safety of brachytherapy treatment is mainly concerned with the calibration of sources and their traceability to internationally accepted Standards. Secondary Standard Dosimetry Laboratory (SSDL) does not offer calibration of ionization chambers with gamma-ray spectrum of high dose rate source 192Ir . This work has been carried out to calibrate the high dose rat...

BACKGROUND The literature supporting high-dose rate brachytherapy (HDR) in the treatment of cervical carcinoma derives primarily from retrospective series. However, controversy still persists regarding the efficacy and safety of HDR brachytherapy compared to low-dose rate (LDR) brachytherapy, in particular, due to inadequate tumor coverage for stage III patients. Whether LDR or HDR brachytherap...

BACKGROUND To report the clinical outcome after a single implant, high dose rate (HDR) brachytherapy in early prostate cancer. MATERIALS AND METHODS All clinically localized prostate cancer patients who underwent high-dose rate (HDR) brachytherapy as monotherapy (no external beam radiotherapy) from February 2006 to September 2011 were analyzed prospectively. Acute and chronic toxicity were as...

introduction based on task group no. 43 (tg-43u1) recommendations, water phantom is proposed as a reference phantom for the dosimetry of brachytherapy sources. the experimental determination of tg-43 parameters is usually performed in water-equivalent solid phantoms. the purpose of this study was to determine the conversion factors for equalizing solid phantoms to water. materials and methods t...

Introduction Low dose rate brachytherapy sources have been widely used for interstitial implants in tumor sites, particularly in prostate. Dosimetric characteristics of a new IrSeed 125I brachytherapy source have been determined using the LiF thermoluminescent dosimeter (TLD) chips. Materials and Methods Dose rate constant, radial dose function, and anisotropy function around the IrSeed 125I so...