background: the monte carlo (mc) method is not only used for dose calculations around brachytherapy sources but also for benchmarking treatment planning systems (tps) calculations. materials and methods: three 60co sources of gzp6 brachytherapy unit were simulated using mcnp4c mc code. the radial dose functions were calculated by mc method and gzp6 tps and were compared. results: there was a go...

INTRODUCTION Stage III melanoma, also referred to as regional metastatic melanoma, has five-year survival rates ranging between 40% and 78%. In order to reduce the likelihood of recurrence in this high-risk population, patients undergo resection of primary tumors and all involved nodal basins. Systemic therapy is being pursued in an effort to improve outcome data, but the best strategy has yet ...

INTRODUCTION Accelerated liver function deterioration has been recognized in renal transplant recipients infected with hepatitis C virus (HCV). Although combination therapy with interferon plus ribavirin has been established as the standard treatment for patients with chronic HCV, the high risk of allograft rejection associated with interferon therapy has greatly discouraged the clinical use of...

At the end of 2020, population-based vaccination programs with new generation mRNA-based vaccines began almost all over world. The aim study was to evaluate titer anti-SARS-CoV-2 IgG antibodies against S1 subunit virus’s spike protein as a marker humoral response in 477 patients and concentration interferon-gamma an indicator cellular 28 individuals. In our studies, we used serological enzyme-l...

BACKGROUND Pediatric patients with high-risk surgically resected melanoma are at risk for relapse, yet little is known about these young patients and how they tolerate high-dose interferon therapy. PROCEDURE We reviewed medical records of patients (< or =18 years) with high-risk melanoma referred to the University of Michigan Pediatric Hematology-Oncology service between January 1989 and July...

A dose of 75 mg of azithromycin per kg of body weight per day combined with a dose of 2 micrograms of gamma interferon per day and administered for 10 days protected at least 40% of mice infected with a lethal inoculum of Toxoplasma gondii. Azithromycin administered alone protected less than 10% of the mice; gamma interferon had no protective effect.

Objectives Protosappanin A (PrA) is an effective and major ingredient of Caesalpinia sappan L. The current study was aimed to explore the effect of PrA on atherosclerosis (AS). Materials and Methods Firstly, the experimental model of AS was established in rabbits by two-month feeding of high fat diet. Then, the rabbits were randomly divided into five groups and treated with continuous high li...