BACKGROUND Poly-substituted xanthine derivatives are an important class of compounds in medicinal chemistry. Substitution at the 8-position of the purine ring is generally accessible by ring closure of a carboxamido-substituted uracil precursor. Although several procedures to accomplish this synthetic step have been suggested, it still remains difficult in many cases. RESULTS Ring closure rea...

This report discloses a mild and efficient O-acetylation using easily accessible TMSOAc as novel acetyl reagent O-trimethylsilylation HMDS for various alcohols catalyzed by tunable Brønsted acidic ionic liquids (TBAILs). Imidazolium-based TBAILs were prepared two-step atom-economic reaction acidities measured UV-visible spectroscopy. Both protections accomplished at room temperature with good t...

Metalloporphirins; Cu(TPP), Mn(TPP)Cl, CO(TPP), Fe(TPP)Cl, zn(TPP) and Mn(OBP)Cl catalyze region and chemoselective silylation of hydroxyl groups with HMDS. Fe(TPP)Cl is the most effective catalyst and silylation occurs immediately in its presence at room temperature.

Area-selective atomic layer deposition (AS-ALD) is a coveted method for the fabrication of next-generation nano-electronic devices, as it can complement lithography and improve alignment through scale control. Selective reactions small molecule inhibitors (SMIs) be used to deactivate growth on specific surface areas such enable AS-ALD. To investigate new applications ASD, we need insight into S...

A surface-acoustic-mode aluminum nitride (AlN) transducer is utilized to determine the type of liquid dropped on the propagation path. It is based on tracking the shrinking droplet radius and observing stagnant liquid molecules during and after the liquid evaporation process. The device configuration is suitable to test small amounts of liquids, in the microliter range. According to both mass l...

The synthesis and characterisation of several sodium zincate complexes are reported. The all-alkyl monomeric sodium zincate, (PMEDTA)·Na(μ-CH2SiMe3)Zn(t)Bu22, is prepared by combining equimolar quantities of (t)Bu2Zn, (n)BuNa and PMDETA (N,N,N',N'',N''-pentamethyldiethylenetriamine)]. A similar approach was used to prepare and isolate the unusual dimeric zincate [(PMEDTA)·Na(μ-(n)Bu)Zn(t)Bu2]23...