BACKGROUND Mental distress among medical students is often reported. Burnout has not been studied frequently and studies using interviewer-rated diagnoses as outcomes are rarely employed. The objective of this prospective study of medical students was to examine clinically significant psychiatric morbidity and burnout at 3rd year of medical school, considering personality and study conditions m...

OBJECTIVE To assess the exposure to different stressors and the prevalence of depression among medical students at different levels of education, taking gender differences into account. DESIGN Students were asked to complete a new stress inventory called the Higher Education Stress Inventory (HESI), the Major Depression Inventory (MDI), slightly modified, and questions on suicidal ideation de...

The rodent Pig-a assay is a flow cytometric, phenotype-based method used to measure in vivo somatic cell mutation. An Organization for Economic Co-operation and Development (OECD) test guideline currently being developed support routine use of the regulatory purposes (OECD project number 4.93). This article provides advice on best practices designing conducting studies evaluating substance safe...

applied optimal control and estimation: digital design and applied optimal control and estimation digital design and applied optimal control and estimation digital design and applied optimal control and estimation; digital design and applied optimal estimation amobbs edexcel physics paper 2 november 2012 elosuk 240ar014 optimization in control & robotics upc dsps for real-time sensing and contr...

DNA microarrays and related tools offer promise for identification of pathways involved in toxic responses to xenobiotics. To be useful for risk assessment, experimental data must be challenged for reliability and interlaboratory reproducibility. Toward this goal, the Hepatotoxicity Working Group of the International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HE...