The rhizome of Phragmites australis has long been used for the treatment of hepatitis in traditional Chinese medicine. In this study, the hepatoprotective and antioxidant activities of an aqueous extract from the rhizome of P. australis (AE-PA) were evaluated. The acute toxicity test in mice showed that AE-PA was nontoxic since a dose of 2000 mg/kg body weight (b.w.) did not cause toxic symptom...

The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous extracts of various parts of the plant such as leaf, stem and root were tested at the dose of 200mg/kg body weight orally using Wistar albino rats and Silymarin was given as re...

The hepatoprotective activity of red grape seed extracts (GSEs) was investigated against ethanol-induced cytotoxicity. In this study, liver slice culture model was used to demonstrate hepatoprotective activity of two GSEs (water and ethanol) in vitro. The hepatoprotective activity was evaluated by measuring the levels of lipid peroxidation, protein carbonyls, lactate dehydrogenase (LDH) leakage...

The objective of the present study was to investigate the hepatoprotective activity of methanol extract of Euphorbia neriifolia (MEEN) against paracetamol induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats by oral administration of paracetamol (640 mg/kg suspended in 1% carboxy methyl cellulose), once during the 16 days treatment period. MEEN was administered orally at the doses ...

BACKGROUND A number of medicinal plants and there compounds played a major role in the treatment of hepatic disorders. They were widely used for the treatment of these disorders, and oxidant stress injury was one of the liver injury mechanisms. The present study evaluated the antioxidant activity and the hepatoprotective effect of each extracts of Phlomis maximowiczii. MATERIALS AND METHODS T...

The strawberry (Fragaria ananassa) has been extensively used to treat a wide range of ailments in many cultures. The present study was aimed at evaluating the hepatoprotective effect of strawberry juice on experimentally induced liver injury in rats. To this end, rats were introperitoneally injected with carbon tetrachloride (CCl4) with or without strawberry juice supplementation for 12 weeks a...

Liver is an important part in human beings and plays a very major role metabolism excretion of xenobiotics from the body. Further, hepatotoxicity caused by different types toxic chemicals, such as antibiotics chemotherapeutic agents, paracetamol (C8H9NO2), thioacetamide (C2H5NS), carbon tetrachloride (CCl4), silymarin (C25H22O10), ethanol (C2H5OH) excessive alcohol intake microbes well research...