results the study found that 72 patients, 43 males and 29 females, had documented hcv infections. age’s ranged from 20 - 75, with a mean of 48. the largest number of patients had the 1a genotypes (41 patients = 56.9%), followed by 3a (25 patients = 34.7%), and 1b and 4a each of them (3 patients = 4.2%). conclusions the study showed that genotypes 1a and 3a are the most common genotypes in patie...

background and objectives: hepatitis c virus (hcv) infection is a worldwide concern and it is the major cause of liver disease. several genotypes of the hcv have been reported from different regions of the world. the determination of the hcv genotypes is important for the prediction of response to antiviral treatment and clinical outcomes. so, hcv genotyping in each region is of great importanc...

results in patients with an svr, the serum levels of aminotransferases were decreased after hcv eradication. although general liver functional tests (albumin and total bilirubin) did not significantly change, the btr values significantly increased. however, in patients without an svr, an improvement in the btr value was not observed after ifn treatment. conclusions hcv eradication can improve t...

conclusions it is suggested that determination of the target genotype by plasma subtyping for choosing the proper antiviral therapy is essential but may result in therapy failure. hcv genotyping in pbmc samples, along with plasma specimens, might be more beneficial. therefore determining the hcv genotype in pbmcs, before beginning the therapy is useful due to the possibility of occult infection...

context hepatitis b and hepatitis c (hbv and hcv) infections are both major causes of hepatocellular carcinoma (hcc). however, hcc caused by each of these two viruses has unique characteristics that should be studied independently to that of another one. while hbv- and hcv-related hccs share similar host and environmental risk factors such as male gender, age above 50 years old, family history ...

background: hepatitis c (hcv) is increasing worldwide including iran. hcv is more prevalent among intravenous drug abusers (idu), especially if imprisoned, mostly due to needle sharing. we determined the rate of hcv seropositivity among idu prisoners and compared it with those of non prisoners. materials and methods: a cross-sectional survey was done on consenting idu inhabiting two prisons and...

background: the human t-cell lymphotropic virus type i is the first retrovirus idenfied in humans. the virus has been associated with adult t-cell leukemia/lymphoma, human t-lymphotropic virus type i, myelopathy/tropical spasc paraparesis, uveis, arthris, pulmonary lymphocyc alveolis, keratoconjuncvis sicca, and infecous dermas. human t-lymphotropic virus type iis endemic in japan, p...

introduction: blood derived products have been known as an effective treatment for many years. however, this treatment is not without risk of infections transmission including hepatitis b virus (hbv) and hepatitis c virus (hcv) and human immune-deficiency virus (hiv) in people who received the blood. nevertheless, due to a high risk of blood born diseases through blood transfusion, screening fo...

results of 351 patients, 76 patients (group 1) had a strong positive result for salivary occult blood test and 275 patients (group 2) had weak positive or negative test results. significant factors between the groups were obesity, level of ast, alt, ldh, alp, alb, d.bil, t.cho, afp, platelets (plt), iri, homa-ir, current interferon (ifn) treatment and the daily frequency of tooth brushing. betw...

influenza c virus possesses specific neuraminate-o-acetylesterase as a receptor-destroying function. this enzymatic activity of the viral glycoprotein hef (hemagglutinin, esterase activity and fusion factor) can be visualized in situ by the use of distinct color substrates. hereby the localization, as well as the quantity of synthesized hef protein is detectable. we further developed the estera...