نتایج جستجو برای: hepatic cells
تعداد نتایج: 1461495 فیلتر نتایج به سال:
background: the hepatic secretion of apolipoprotein b (apob), containing lipoproteins, is known to be regulated by insulin, and the overproduction of these atherogenic lipoproteins occurs in insulin-resistant states. protein tyrosine phosphatase 1b (ptp-1b) is a key regulator of hepatic insulin signaling and is also upregulated in insulin resistance. we aimed to investigate the role of ptp-1b i...
Background and purpose: Infection caused by hepatitis B virus is a major health problem and the most common known chronic infection. It has an important role in developing cirrhosis and hepatic cancer. Glutathione-s-transferase enzyme is one of the most important metabolic enzymes in cellular protection mechanisms such as: xenobiotic detoxification and metabolism and cells protection again...
many hepatoprotective herbal preparations have been recommended in alternative systems of medicine for the treatment of hepatic disorders. no systematic study has been done on protective efficacy of capparis spinosa (capparidaceae) to treat hepatic diseases. protective action of c. spinosa ethanolic root bark extract was evaluated in this study in an animal model of hepatotoxicity, which was in...
HCC is marked by genetic heterogeneity and activated hepatic stellate cells (HSC) are considered key players during development. The paracrine effect of different cell lines on the activation primary hHSC was accompanied differential AMPK depending line used. Pharmacological treatment inhibited HCC-induced through AMPK-dependent AMPK-independent mechanisms. This heterogenic confirmed data minin...
Hepatic stellate cells are believed to play a key role in the development of liver fibrosis. Several studies have reported that bone marrow cells can give rise to hepatic stellate cells. We hypothesized that hepatic stellate cells are derived from hematopoietic stem cells. To test this hypothesis, we generated chimeric mice by transplantation of clonal populations of cells derived from single e...
BACKGROUND Progressive liver fibrosis is the result of chronic liver injury and is characterized by the excessive accumulation of extracellular matrix that may result in liver failure. Activated hepatic stellate cells are known to play a central role in this process and their elimination is a crucial step towards the resolution and reversion of liver fibrosis. In the present study, we investiga...
Hepatic coccidiosis is considered as a major problem in rabbits which mortality rate may go high as a result of unhygienic maintenance with overcrowding. This study was aimed to determine abundance and pathologic changes of hepatic coccidiosis in rabbits of northwestern Iran. A total of 320 rabbits (110 New Zealand, 110 Angora, and 100 Native) in different sex and age groups were randomly selec...
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