نتایج جستجو برای: hemojuvelin mutation
تعداد نتایج: 291556 فیلتر نتایج به سال:
BACKGROUND Sex-related differences in cardiac function and iron metabolism exist in humans and experimental animals. Male patients and preclinical animal models are more susceptible to cardiomyopathies and heart failure. However, whether similar differences are seen in iron-overload cardiomyopathy is poorly understood. METHODS AND RESULTS Male and female wild-type and hemojuvelin-null mice we...
BACKGROUND The circulating hormone hepcidin plays a central role in iron homeostasis. Our goal was to establish an ex vivo iron-sensing model and to characterize the molecular mechanisms linking iron to hepcidin. DESIGN AND METHODS Murine hepatocytes were isolated by the collagenase method, either from wild type or HFE knockout mice, and cultured 42 h without serum before treatments. RESULT...
This article has been retracted at the request of the authors.
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