نتایج جستجو برای: hemoglobinuria
تعداد نتایج: 2365 فیلتر نتایج به سال:
BACKGROUND Paroxysmal nocturnal hemoglobinuria (PNH) arises from a somatic mutation of the PIG-A gene in a hematopoietic stem cell and the subsequent production of blood cells with a deficiency of surface proteins that protect the cells against attack by the complement system. We tested the clinical efficacy of eculizumab, a humanized antibody that inhibits the activation of terminal complement...
Dural sinus thrombosis developed in two young women with paroxysmal nocturnal haemoglobinuria (PNH). The incidence, the clinical presentation, the radiologic findings, the therapy and the pathophysiology of haemolysis and thrombosis are discussed.
s 2008;112:407.
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