hemoglobin is a tetrameric oxygen transport protein in animal bodies. however, there is a paucity of information regarding differences between alpha and beta subunits of hemoglobin in terms of oxygen affinity. the sequential model of koshland, nemthy and filmer (knf model) has attributed similar affinities to both alpha and beta subunits. the main purpose of the present study is to construct a ...

conclusions the association of the 1st trimester high hb and hct with preeclampsia was revealed in this study, therefore it could be used as a prediction factor for early preeclampsia diagnosis. results preeclampsia incidence was 5.1% in our study. mean hb was 12.38 ± 1.69 g/dl in the preeclampsia group and 11.8 ± 1.18 in the non-preeclampsia group, and mean hct was 37.74 ± 5.15% in the preecla...

Haemophilus influenzae requires heme for growth and can utilize hemoglobin and hemoglobin-haptoglobin as heme sources. We previously identified two hemoglobin- and hemoglobin-haptoglobin-binding proteins, HgpA and HgpB, in H. influenzae HI689. Insertional mutation of hgpA and hgpB, either singly or together, did not abrogate the ability to utilize or bind either hemoglobin or the hemoglobin-hap...

Abstract Background Anemia is one of the most common abnormalities in pediatric medicine. Considerable differences are seen in the peripheral blood indices of infants in developing countries. The aim of this study was to determine and compared blood hemoglobin concentration in three sites of sampling in neonate. Materials and Methods 1600 term and preterm new infant in three sites of sampli...

hepatic dysfunction is a frequent manifestation in patients with sickle cell anemia. it is usually a multifactorial process. a rare benign form of extreme hyperbilirubinemia, presumably due to intrahepatic sickling, may be the cause. we report a 9 year old girl with sickle-thalassemia hemoglo binopathy, presenting with profound jaundice. sickle cell disease is often mild in the iranian populati...

conclusions apc referral for elevated hba1c reduces complication rate and the incidence of prolonged hospitalization during the first year after surgery in diabetics undergoing tja. results patients (197 men, 6 women) underwent 71, 131, and 1 total hip, knee, and shoulder replacements, respectively. patients undergoing tja with uncontrolled hba1c and those with hba1c < 10%, but not those with h...