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the use of magnetic fields in targeted drug delivery, especially for treatment of cancers and tumoral regions, is one of the significant techniques in the field of modern methods of treatment. considering that many vital biological tissues have been located deep in the body, then for targeted drug delivery and effective treatment in these tissues, it is required to bring therapeutic agent to th...

OBJECTIVE Assess outcome in children treated with inotrope, vasopressor, and/or vasodilator therapy for reversal of fluid-refractory and persistent septic shock. DESIGN Survey; case series. SETTING Three pediatric hospitals. PATIENTS Fifty consecutive patients with fluid-refractory septic shock with a pulmonary artery catheter within 6 hours of resuscitation. INTERVENTIONS Patients were...

BACKGROUND Cardiac transplantation faces the serious problem of lack of donors and it is estimated that 20 to 40% of the patients die while waiting for heart transplantation. For these patients, the use of mechanical circulatory assist devices is the only choice of survival while waiting for a donor. In Brazil, the experience with mechanical circulatory support is limited and there is no regula...

In epilepsy it has been challenging to detect early changes in brain activity that occurs prior to seizure onset and to map their origin and evolution for possible intervention. Here we demonstrate using a rat model of generalized epilepsy that diffuse optical tomography (DOT) provides a unique functional neuroimaging modality for noninvasively and continuously tracking such brain activities wi...

Adequate oral or intravenous doses of a betaadrenergic receptor-blocking drug, nethalide,' produce no significant changes in the resting oxygen consumption, heart rate, cardiac output, and systemic mean arterial or mean right atrial pressures of patients with spontaneous hyperthyroidism (1). These findings do not support the concept that the hemodynamic changes in hyperthyroidism are mediated t...

The progression of a cerebral aneurysm involves degenerative arterial wall remodeling. Various hemodynamic parameters are suspected to be major mechanical factors related to the genesis and progression of vascular diseases. Flow alterations caused by the insertion of coils and stents for interventional aneurysm treatment may affect the aneurysm embolization process. Therefore, knowledge of hemo...

Introduction: One of the most common problems during laryngoscopy involves sympathetic system stimulation and the subsequent hemodynamic changes. It is a key measure to maintain the hemodynamic stability of patients with cardiovascular diseases during induction of anesthesia. This study attempted to compare the hemodynamic effects of laryngeal mask airway and combitube. Methods: This prospec...