Abstract Biosynthesis of nanoparticles is the preferred route for fabrication biocompatible and cheaper drugs. In this study, extract major secondary metabolite from Helichrysum aureonitens , 3,5-dihydroxy-6,7,8-trimethoxyflavone, were used to synthesize silver zinc oxide nanoparticles. Spectroscopic microscopic techniques confirmed formation The flavone alone showed higher DPPH radical scaveng...