BACKGROUND Antiemetic triplet therapy including dexamethasone (DEX) is widely used for patients receiving highly emetogenic chemotherapy (HEC). In Japan, the appropriate dose of DEX has not been established for this combination. MATERIALS AND METHODS To assess the efficacy and safety of increased-dose DEX, we retrospectively examined patients receiving HEC with antiemetic triplet therapy. R...

A thermosensitive polymer can be held liquid before being injected to deliver living cells or therapeutic agents and formed monolithic gels when injected in vivo. In this study, chitosan-based thermosensitive hydrogels were prepared, characterized and the biocompatibility for culturing mice bone mesenchymal stem cells (BMSC) on 2D films and within 3D hydrogel were investigated. The gelation tem...

The U.S. Army Corps of Engineers’ Hydrologic Engineering Center’s River Analysis System (HEC-RAS) is a widely used software application for performing one-dimensional and two-dimensional steady and unsteady flow river hydraulics calculations, sediment transport-mobile bed modeling, and water quality analysis. User’s of HEC-RAS have often unique applications including the coupling with other sof...

Many cities have been built along large rivers. The rivers can provide a source of drinking water, act as receiving water for treated effluent, provide navigation for shipping, and other beneficial uses. However, the city must also be protected from flooding due to the close proximity to the river. Hydrologic analysis plays a crucial role in the development of plans for protecting a river city....

OBJECTIVES In this study, we have established an in vitro three-dimensional (3D) coculture, where normal endometrial stromal cells and endometrial cancer cells were cocultured under defined hormonal conditions, to investigate the potential paracrine effects on synthesis and secretion of matrix metalloproteinases (MMPs) and, thus, cancer invasion. METHODS Endometrial stromal cells were obtaine...

In this paper, we present a conceptual framework of human–elephant conflict (HEC) management embodying community aspects gleaned from the importance–performance analysis (IPA) for National Park in Vietnam. Nine approaches were proposed to prevent and mitigate HEC (HEC indicators), which six fell into different quadrants based on respective estimations farmer non-farmer respondents. Both levels ...

Delivery Traveling Salesman Problem with LIFO Loading Francesco Carrabs Dipartimento di Matematica ed Informatica, Università di Salerno, 84084 Fisciano (SA), Italy [email protected] Jean-François Cordeau Canada Research Chair in Logistics and Transportation and Center for Research on Trasportation HEC Montréal, 3000 chemin de la Côte-Sainte-Catherine, Montréal, Canada H3T 2A7 [email protected]...

This paper proposes a novel hybrid equalizer circuit (HEC) for battery management system (BMS) to implement the passive HEC (P-HEC), active (A-HEC), or active/passive (AP-HEC) with same architecture. The advantages of an are that it is simple, cost-effective, highly energy efficient, and fail safe. P-HEC can further use cooling fan heater instead conventional resistor as power dissipation eleme...

Linearized versions of the Nelson-Siegel (1987) and Svensson (1994) models for the cross-sectional estimation of spot yield curves from samples of coupon bonds are developed and analyzed. It is shown how these models can be made linear in the level, slope and curvature parameters and how prior information about these parameters can be incorporated in the estimation procedure. The performance of...

This paper describes the first use of frequency-domain fluorescence lifetime for multiplex detection of DNA restriction fragments in capillary electrophoresis (CE). The fragments were labeled with monomeric intercalating dyes that can be excited by either the 488- or 514-nm line of an argon ion laser and have lifetimes in the range of 0.5-2.5 ns. We were able to achieve multiplex lifetime detec...