Microperforated membranes are essential components of various organ-on-a-chip (OOC) barrier models developed to study transport molecular compounds and cells across cell layers in e.g. the intestine blood-brain barrier. These OOC have two functions: 1) support growth on one or both sides, 2) act as a filter-like separate adjacent compartments. Thin, microperforated poly(dimethylsiloxane) (PDMS)...

background: the adjuvanticity potential of lactobacillus casei was first suggested in an old survey. the present study was designed to investigate the efficacy of a new immunotherapy against breast cancer made by mixing an extract of heated 4t1 mammary carcinoma cell line and a heat-killed preparation of lactobacillus casei. methods: female balb/c mice (6–8 weeks old, n=40) were challenged subc...

BACKGROUND Heated breathing tubes were developed to improve heated humidification in continuous positive airway pressure (CPAP) therapy of patients with obstructive sleep apnea syndrome (OSAS). OBJECTIVES We wanted to investigate the influence of a heated breathing tube on patients' satisfaction with the treatment, the rate of side effects and the adherence to treatment. METHODS Eighty-eigh...

Oxidized unsaturated fatty acids may contribute to the pathogenesis of atherosclerosis. In the present study, we examined the effects of heated palm oil mixed with 2% cholesterol diet on serum lipid profile, homocysteine and thiobarbituric acid reactive substances (TBARS) levels in estrogen-deficient rats. Twenty-four female Sprague Dawley rats were ovariectomized and then were divided equally ...

Sera (920) were tested to evaluate the use of heated versus unheated sera in the hemagglutination treponemal test for syphilis. The heated and unheated samples were tested on the same day with the hemagglutination treponemal test for syphilis kit according to the manufacturer's protocol. Agreement of results between the heated and unheated sera was 99.2%. The reading pattern of agglutination wa...

OBJECTIVES To retrospectively collect data on patients with burn injury due to hot depilatory wax. To investigate the effect of varying microwave output power on wax temperature. To determine whether instructions provided by manufacturers allow safe domestic use. METHODS Data from the RAH burns database was collected for patients with wax-induced burns between January 1991 and January 2010. W...

BACKGROUND Fast-acting insulin analogs have been available since 1996. The absorption rate of these insulins is still too slow to mimic the physiological insulin action in healthy subjects. This study investigates the clinical performance of InsuPatch™, a local skin-heating device, on postprandial glucose excursion. METHODS Twenty-four type 1 diabetes mellitus subjects on continuous subcutane...

BACKGROUND Hen's egg allergy is a frequent cause of childhood food allergy. Egg yolk is used in various commonly consumed foods; if children with allergy to hen's egg could eat heated egg yolk, their quality of life (QOL) would improve. No reports exist regarding oral food challenges (OFCs) for heated egg yolk. We aimed to clarify whether pediatric patients allergic to hen's egg could consume h...

INTRODUCTION Wheat bags are therapeutic devices that are heated in microwaves and commonly used to provide relief from muscle and joint pain. The Royal Adelaide Hospital Burns Unit has observed a number of patients with significant burn injuries resulting from their use. Despite their dangers, the products come with limited safety information. METHODS Data were collected from the Burns Unit d...