BACKGROUND In healthy individuals slow temporal summation of pain or wind-up (WU) can be evoked by repetitive heat-pulses at frequencies of ≥.33 Hz. Previous WU studies have used various stimulus frequencies and intensities to characterize central sensitization of human subjects including fibromyalgia (FM) patients. However, many trials demonstrated considerable WU-variability including zero WU...

The cytotoxic effects of short duration, high temperature, and long duration, low temperature hyperthermia were determined in human cells growing in culture. The human tumor cell lines A549 (lung carcinoma). VV'iDr(colon carcinoma), and U87MG (glioblastoma) were used. In addi tion, a normal human lung fibroblast cell type 18Lu was used. Sensitivity to direct cell killing was measured at 41, 43,...

Adsorption and heat inactivation studies were made on a series of host range, turbid (ht) mutants of coliphage T2H to determine the mechanisms of phenotypic expression of these genes and of the additivity of gene effects. The ht mutants adsorb to the resistant cell B/2H at a slower rate than the clear h mutant; double and triple ht mutants adsorb with increased efficiency. Some mutants show inc...

Postharvest heat treatments lead to an alteration of gene expression and fruit ripening can sometimes be either delayed or disrupted. The extent of the alternation of fruit ripening is a function of the exposure temperature and duration and how quickly the commodity is cooled following the heat treatment. The most commonly measured components of fruit ripening affected by heat treatments includ...