The interrelation between the loudness of the first heart sound, the time interval from the Q wave to the onset of the first heart sound (QM1), and the mitral valve closure rate was studied in nine patients presenting with left atrial myxomata. In seven patients the first heart sound was loud preoperatively and was associated with delayed mitral valve closure. After removal of the myxoma the on...

Heart valve disease is a very common medical condition; the most frequent aetiology is degenerative valve disease, mainly represented by calcific aortic stenosis in the elderly. In developing countries, valvular heart disease triggered by rheumatic fever is the most important aetiology and can lead to a heterogeneous heart valve disease, mainly represented by mitral stenosis in young female pat...

A2-year-old cachectic cross-breed gelding was admitted toVeterinary Teaching Hospital of University of Tehran followingthe onset of a marked respiratory distress, coughing and ventraledema. Clinical examinations indicated harsh respiratory andexpiratory sounds as well as jugular vein distention. Therespiratory and heart rates were 35/min and 60 bpm, respectively.Agrade III/IV pansystolic murmur...

INTRODUCTION AND OBJECTIVES There have been no studies conducted in the past that focus on the significance of congestive heart failure in patients with prosthetic valve endocarditis. We studied the incidence of congestive heart failure in patients with prosthetic valve endocarditis and analyzed its profile. In this study, we addressed the prognostic significance of heart failure in patients wi...

Bioprosthetic valve use has increased significantly. Considering their limited durability, there will remain an ongoing clinical need for repairing or replacing these prostheses in the future. The current standard of care for treating bioprosthetic valve degeneration involves redo open-heart surgery. However, repeat cardiac surgery may be associated with significant morbidity and mortality. Wit...

Each heart valve is composed of different structures of which each one has its own histological profile. Although the aortic and the pulmonary valves as well as the mitral and the tricuspid valves show similarities in their architecture, they are individually designed to ensure optimal function with regard to their role in the cardiac cycle. In this article, we systematically describe the struc...

1. Artificial heart valves have been in use for over five decades to replace diseased heart valves. Since the first heart valve replacement performed with a caged-ball valve, more than 50 valve designs have been developed, differing principally in valve geometry, number of leaflets and material. To date, all artificial heart valves are plagued with complications associated with haemolysis, coag...

PURPOSE: Patient-specific heart and valve models have shown promise as training and planning tools for heart surgery, but physically realistic valve models remain elusive. Available proprietary, simulation-focused heart valve models are generic adult mitral valves and do not allow for patient-specific modeling as may be needed for rare diseases such as congenitally abnormal valves. We propose c...

BACKGROUND The bicaval technique for orthotopic heart transplantation decreases the incidence of tricuspid valve regurgitation when compared with the standard biatrial technique. This study was designed to study the effects of prophylactic tricuspid valve annuloplasty during bicaval orthotopic heart transplantation on survival, renal function, and amount of tricuspid valve regurgitation. METH...

Reference to this organ, which perhaps was not commonplace in the scientific literature 15 years ago, has become exceedingly prevalent in the past 5 years. The field of heart valve research has become contemporary due to a heightened awareness of the seriousness and frequency of heart valve disease. Indeed, valve therapies are still extremely limited for patients above the age of 75 or less tha...