Anesthetic management for massive blood loss in liver surgery concomitant with hemodynamic instability secondary to carcinoid crisis can be challenging in the perioperative setting. Hypotension, diarrhea, facial flushing, bronchospasm, and tricuspid and pulmonic valvular diseases are the common manifestations of carcinoid syndrome. This report illustrates the importance of early recognition and...

Carcinoid tumors are uncommon, slow-growing neoplasms. These tumors are capable of secreting numerous bioactive substances, which results in significant potential challenges in the management of patients afflicted with carcinoid syndrome. Over the past two decades, both surgical and medical therapeutic options have broadened, resulting in improved outcomes. The pathophysiology, clinical signs a...

blood pressure cause death from coronary heart disease? Journal of Human Hypertension 1988;2:7-10. 10 Fletcher AE, Beevers DG, Bulpitt CJ, et al. The relationship between a low treated blood pressure and IHD mortality: a report from the DHSS Hypertension Care Computing Group (DHCCP). 12 Hypertension Detection and Follow-up Program Collaborative Group. Hypertension Detection and Follow-up Progra...

We present a case of metastatic recurrence of carcinoid tumor accompanied by carcinoid syndrome in a 68-year-old Japanese man, 12 years after resection of typical pulmonary carcinoid. Histopathologic examination from percutaneous liver biopsy revealed metastatic typical carcinoid. Clinical symptoms gradually improved after administration of octreotide LAR. Two years after starting treatment, th...

In recent years there has been a great deal of interest in the so-called carcinoid syndrome. This syndrome has been observed in many cases of carcinoid tumour of the gastro-intestinal tract with extensive metastasis. It consists of certain transient and permanent vaso-motor changes, bronchoconstriction, hyperperistalsis, oedema and ascites, pellagra, and mural and valvular endocardial sclerosis...

A number of new or hitherto inadequately defined diseases of the heart have been described in recent years. Among these have been subendocardial fibrosis (Thomas et al., 1954), localized outflow tract hypertrophy (Brock, 1957), and viral myocardiopathy (Silber, 1958) as causes of heart failure, and rheumatoid spondylitis (Clark and Bauer, 1948), Marfan's syndrome (McKusick, 1955), and, the carc...

Ectopic production of adrenocorticotropic hormone by carcinoid tumors is relatively uncommon and may not be recognized by physicians. This report describes a woman who had Cushing syndrome from the ectopic secretion of adrenocorticotropic hormone by a carcinoid tumor. Her cause of death was a pneumonia that may have been secondary to her untreated hypercortisolism. There are threeinstructive el...

Carcinoid syndrome (CS), mostly associated with small intestinal neuroendocrine tumors (SI-NETs) or lung-related NETs, is characterized by symptoms related to hormonal secretion and long-term complications, including carcinoid heart disease (CHD), which potentially life-threatening. In the early stages of disease, are non-specific, leads delayed diagnoses. The availability reliable tumor marker...

Gastro-intestinal carcinoids are slow growing tumors arising from enterochromaffin or Kulchitsky cells. Their clinical presentation depends on what combination of bioactive substances is secreted. Midgut carcinoid can present with the carcinoid syndrome in the presence of liver metastases. Its most typical clinical manifestations include cutaneous flushing and diarrhea. A nonspecific biochemica...