BACKGROUND Health services that affect quality of life (QoL) are increasingly evaluated using cost utility analyses (CUA). These commonly employ one of a small number of multiattribute utility instruments (MAUI) to assess the effects of the health service on utility. However, the MAUI differ significantly, and the choice of instrument may alter the outcome of an evaluation. AIMS The present a...

IntroductionIn CheckMate 227 (NCT02477826), patients with treatment-naive stage IV or recurrent NSCLC and 1% greater tumor programmed death ligand 1 expression had significantly improved overall survival nivolumab plus ipilimumab versus chemotherapy. We present the patient-reported outcomes (PROs).MethodsPatients (N = 1189) were randomized to ipilimumab, nivolumab, PROs exploratory. Changes in ...

BACKGROUND Trials have not assessed the effect of dalfampridine-extended release (dalfampridine-ER) on health utility. We sought to evaluate the effect of dalfampridine-ER tablets (prolonged-release fampridine in Europe) on health utility in patients with multiple sclerosis (MS) by mapping subjects' individual item scores from the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) onto the Euro...

topological indices are numerical parameters of a graph which characterize its topology. inthis paper the pi, szeged and zagreb group indices of the tetrameric 1,3–adamantane arecomputed.

conclusions this study indicated that there are major indicators affecting oral health status and it was believed that current study results and suggestions can pave the way for health care planners and policymakers. results the obtained results showed that the average dmft was 7.91 ± 3.78 and one third of the students had symptoms of gingival inflammation, whereas only five percent of them did...

background: despite the enhancement in health outcomes worldwide, health inequity and inequality is one of the most relevant topics both for health policy and public health. this research was designed to decompose the health inequality of people living in shiraz, south-west iran. methods: data were obtained from a multistage-sample survey conducted in shiraz from april to may 2012, to find dete...

background: in this study, we examined the status of korean women’s alcohol consumption and identified the physical changes they undergo according to the level of consumption. the results of this study may thus be used as raw data to effectively control women’ drinking habits. methods: this study consists of a secondary analysis using data from female participants in the 6 th korea national hea...