BACKGROUND In this study we aimed to explore the effects of pregabalin on a traumatic brain injury model in rats. MATERIAL AND METHODS This study included 40 adult male Sprague-Dawley rats randomized into 4 groups, each of which contained equal numbers of animals. The control group had no head trauma and thus was not treated. The trauma group had head trauma but was not treated. The pregabali...

BACKGROUND Trauma is the most common cause ofpaediatric deaths. In 75% ofpaediatric trauma deaths, head injury is responsible, and most are from falls. Recent reports from Nigeria, however, appear to indicate a predominance of road traffic accidents, instead of falls. OBJECTIVE To evaluate the aetiology of paediatric head trauma, management protocols and outcome from our Centre, in order to a...

Background: Motorcyclists are among the most vulnerable groups of road accident victims, who are prone to a growingmortality rate due to the constant rise in the number of accidents. This study was performed to investigate the injurypatterns among motorcyclist trauma patients admitted to Kamyab Hospital, the largest trauma center affiliated withMashhad Univercity of Medical Sc...

Moyamoya vascular pattern and dural arteriovenous fistula (dAVF) are rare vascular abnormalities and both can be secondary to head trauma. The role of dural angiogenesis in the pathophysiology of vascular malformation is rather unclear. We report a unique case of moyamoya vasculopathy simultaneously associated with dAVF after heavy head trauma. It seems that both moyamoya syndrome and dAVFs are...

OBJECTIVE Our study examined the prognostic factors involved in the outcome of patients with chronic subdural hematoma (CSDH) who had undergone burr hole drainage procedures, and investigated the association between outcome and traumatic head injury. In addition, we explored factors related to recurrence. METHODS This study enrolled 238 patients with CSDH who had undergone burr hole drainage....

Olfactory impairment has been shown to be linked to head injury. In addition, it is believed that measurement of olfactory function after head trauma represents a sensitive tool for measuring frontal brain damage. Aim of the study was to evaluate the effect of mild head trauma in children on olfactory function over a time period of up to 1 year after head trauma. The olfactory function of 114 c...

Head trauma leading to brain injury is an important cause of morbidity and mortality in childhood. Injury severity is related to the mechanism of trauma, which itself varies with age. The vast majority of head trauma in paediatric patients is mild, requires no specific therapy and leaves no sequelae. However, it is important to identify individuals at risk of significant injury, and thus in nee...

PURPOSE To evaluate the significance of cavernous sinus gas identified on head CT scans. METHODS Head CT scans were viewed prospectively for a period of 3 years. The charts of patients who demonstrated cavernous sinus gas were reviewed. RESULTS Seventeen patients without head trauma and 10 patients with head trauma demonstrated gas in the cavernous sinus. None of the patients had symptoms o...

BACKGROUND TG6, a brain expressed transglutaminase, is implicated in the neurological manifestations of celiac disease (CD). We hypothesized that earlier brain injury due to head trauma may be more common in patients with CD, potentially through trauma-induced TG6 leading to interaction with TG2. METHODS Through biopsy reports from all 28 pathology departments in Sweden we identified 29,096 i...