The single nucleotide polymorphisms (SNPs) in the BUD13 homolog (BUD13) and zinc finger protein 259 (ZNF259) genes have been associated with one or more serum lipid traits in the European populations. However, little is known about such association in the Chinese populations. Our objectives were to determine the association of the BUD13/ZNF259 SNPs and their haplotypes with hypercholesterolaemi...

AIM To study the effect of different food processing techniques on the degradation of organochlorine compounds (α, β, ɣ and δ hexachlorocyclohexane isomers (HCH)) residues in both natural and fortified samples of milk. MATERIALS AND METHODS Raw milk samples are collected from the local areas of Hyderabad, India. Naturally and fortified milk samples (HCH) were subjected to various food process...

OBJECTIVE Our objective is to explore the effect of platelet infusion, anticoagulant and other risk factors on the rehaemorrhagia after surgery of hypertensive cerebral hemorrhage (HCH), and to provide a reference for the prevention and treatment of rehaemorrhagia in patients with HCH. PATIENTS AND METHODS The patients with HCH admitted during April, 2007-June, 2012 in our hospital were selec...

Organochlorine pesticide (OCP) cycling was studied in the area of Banja Luka, Bosnia and Herzegovina, over 3 days in summer with high temporal (4 h-means) and spatial (3 sites distanced 3-6 km) resolutions. Elevated levels of DDX compounds (i.e. o,p'- and p,p'-isomers of DDT, DDE and DDD, 44-74 pg m(-3) at the urban sites and 27 pg m(-3) as a background level), HCH (α-, β- and γ-isomers, 52-70 ...

AIM A study to assess the toxic effects of gamma-hexachlorocyclohexane (γ-HCH) (lindane) and ameliorative effects of Camellia sinensis on renal system has been carried out in male Wistar rats. MATERIALS AND METHODS Four groups of rats with 18 each were maintained under standard laboratory hygienic conditions and provided feed and water ad libitum. γ-HCH was gavaged at 20 mg/kg b.wt. using oli...

تمام ترکیبات اورانیم، سمی و رادیواکتیو هستند. بودن این عنصر می‌تواند کشنده باشد. با توجه به سمیت شیمیایی رادیواکتیویته ضروری است از ورود آن طبیعت جلوگیری شود. پسماندهای خروجی مراکز صنعتی- هسته­ای نیز دارای مقادیر مختلفی اورانیم می­باشد لذا حذف پساب اهمیت ویژه­ای برخوردار است. سویی دیگر، نظر محدودیت منابع آن، بازیابی پسماندها، ارزش اقتصادی می­باشد. در پژوهش حاضر، روش سطح پاسخ (RSM) بر اساس طرح م...

Hypochondroplasia (HCH) is an autosomal dominant inherited skeletal dysplasia, usually caused by a heterozygous mutation in the fibroblast growth factor receptor 3 gene (FGFR3). A 27-year-old HCH woman with a history of two consecutive abortions of HCH-affected fetuses visited our clinic for preimplantation genetic diagnosis (PGD). We confirmed the mutation in the proband (FGFR3:c.1620C>A, p.N5...

The gap junction protein connexin 43 (Cx43) exhibits dynamic trafficking that is altered in most tumor cells and in response to carcinogen exposure. A number of connexin (Cx)-binding proteins are known to be involved in endocytic internalization of gap junctions. Here, we analyzed the discrete molecular interactions that occur between Src, ZO-1 and Cx43 during Cx43 internalization in response t...

0045-6535/$ see front matter 2008 Elsevier Ltd. A doi:10.1016/j.chemosphere.2008.04.047 * Corresponding author. Present address: School of Technology, Department of Oceanography, Universit Pope Road, Honolulu, HI 96822, USA. Tel.: +1 808 956 E-mail address: [email protected] (T. Ilyina) Mass budgets of hexachlorocyclohexanes (a-HCH and c-HCH) and a polychlorinated biphenyl (PCB 153) for 1...