Background: Tooth avulsion implies total displacement of the tooth out its socket. Many storage media such as milk, saliva, Hank’s Balanced Salt Solution (HBSS), propolis, Viaspan, have been studied medias for preserving PDL cell viability. Amongst these, HBSS has proposed medium choice treatment avulsed teeth by American Associations Endodontists. However, major disadvantage is that it not eas...

OBJECTIVE To study degrees of chronic kidney disease (CKD) using creatinine clearance in adult Nigerian patients with sickle-cell disease (SCD). METHODS One hundred SCD patients, made up of 79 HbSS (homozygous haemoglobin S) patients and 21 HbSC (heterozygous haemoglobins S and C) patients, were investigated prospectively, along with 50 normal controls. Their sociodemographic data, weight and...

Cerebrovascular accident (CVA) is a common, devastating neurological complication of sickle cell disorder (SCD) with a high recurrent and mortality rate. The Stroke Prevention Trial in Sickle Cell Anaemia study (STOP) recommends routine screening with transcranial Doppler ultrasonography in children aged two to sixteen years with SCD. The present study assessed cerebral blood flow velocities of...

Hepatitis B virus (HBV) infection remains a global public health challenge with an estimated 257 million people in 2015 living as chronic carriers. Sub-Saharan Africa has the second largest burden of these carriers HBV infection. Children sickle cell anemia (HBSS) are prone to recurrent blood transfusion attendant risk blood-borne diseases including hepatitis There several studies Nigeria on pr...

Holistic care of patients with sickle cell anaemia (HbSS) was carried out in a dedicated support group and clinic in Lagos. This paper examines the outcome of this initiative using mortality, hospital admission and blood transfusion rates from inception in April 1988 to December 1995. Patients with sickle cell disorder and their families were admitted to the Sickle Cell Club and its associated ...

OBJECTIVE The purpose of this study was to use a Collagenase-Dispase assay to investigate the potential of a new storage media, coconut water, in maintaining viable periodontal ligament (PDL) cells on simulated avulsed teeth. STUDY DESIGN Fifty freshly extracted human teeth were divided into 3 experimental groups and 2 control groups. The positive and negative controls corresponded to 0 minut...

STATEMENT OF THE PROBLEM The maintenance of viable periodontal ligament cells is the most important issue in the long-term preservation of avulsed teeth. PURPOSE The aim of this study was to assess aloe vera as a new storage media in maintaining the cell viability of dry-stored teeth in comparison with soy milk, Hank`s balanced salt solution (HBSS), and milk. MATERIALS AND METHOD Twenty one...

CONTEXT Premarital haemoglobin screening is an important strategy for the control of Sickle Cell Disease. AIMS To determine the prevalence and pattern of sickle cell disease among premarital couples and to assess their attitude to the risk of sickle cell anaemia in their offspring. SETTINGS AND DESIGN A cross sectional descriptive study using interviewer administered questionnaire and haemo...

BACKGROUND Fetal hemoglobin (HbF) levels in different hemoglobin variants in Osogbo, Nigeria, were estimated using two principal methods of estimation using existing information for HbF concentration and distribution of various hemoglobin variants in the area, as well as diagnosed cases of thalassemia. Two hundred and sixty samples collected from HbSS, HbSC, HbAA, HbAS, and HbAC subjects were a...

Objective: The present study aims to describe ocular alterations in sickle cell disease patients in Bahia, a Northeast state, with the highest prevalence of the disease in Brazil. Methods: We carried out a cross-sectional study in a group of 146 (292 eyes) sickle cell disease patients (90 HBSS and 56 HBSC). Ophthalmologic examination including indirect binocular ophthalmoscopy was performed. Ex...