background & objectives: hepatitis b is one of the major health problems in the world. health care workers (hcws) are at high risk of acquiring hepatitis b virus. the aim of this study was to evaluate the prevalence of hbv infection and the immune response to hbv vaccine among the hcws in babol, northern iran. methods: this study was accomplished on 527 hcws and administrative staff working...

background: for healthcare workers, sometimes the conventional hepatitis-b virus (hbv) vaccination schedule might not provide seroconversion rapidly enough. the aim of this study was to compare the efficacy of conventional hbv vaccination with an accelerated schedule (days 0-1-21). normal 0 false false false en-us x-none ar-sa materials and methods: in this randomized clinical trial, 161 health...

Neonatal immunization with hepatitis B (HB) vaccine is highly effective; however, more needs to be learned about the duration of protection and indications for boosters. We measured antibody to HB core antigen (anti-HBc), HB surface antigen (HBsAg), and pre- and postbooster titers of HBsAg antibody (anti-HBs) 15 years after primary neonatal immunization with plasma-derived HB vaccines in 2 coho...

BACKGROUND Current consensus does not support the use of a universal booster of hepatitis B virus (HBV) vaccine because there is an anamnestic response in almost all children 15 years after universal infant HBV vaccination. We aimed to provide a booster strategy among adolescents as a result of their changes in lifestyle and sexual activity. METHODS This study comprised a series of cross-sect...

background it is important to differentiate whether isolated anti-hbc is due to false positive results or the prior exposure to hepatitis b virus, because individuals with false-positive anti-hbc can benefit from vaccination and their blood can be safely transfused. to distinguish between these two conditions, we evaluated the serologic response to hepatitis b vaccine. methods ninety subjects w...

BACKGROUND Sub-Saharan Africa has a high prevalence of hepatitis B virus (HBV) infections. Health care workers (HCWs) are at high risk of contracting HBV infection through their occupation. Vaccination of HCWs against HBV is standard practice in many countries, but is often not implemented in resource-poor settings. We aimed with this cross-sectional study to determine HBV prevalence, HCW vacci...

Background: Chemokine genetic variations are involved in infectious diseases such as hepatitis B virus (HBV). Several allelic variants might, in theory, affect the outcome of vaccination. Objectives: This study was carried out to examine the associations of Δ32 CCR5 and 190G > A CCR2 polymorphisms with a response to a primary course of three HBV vaccinations. Methods: Between December 2014 and ...

BACKGROUND A two-dose preoperative vaccination schedule against HBV has been the widely accepted policy in Poland. However, its effectiveness has not yet been assessed. OBJECTIVE To evaluate a two-dose preoperative HBV vaccination policy by an assessment of the proportion of patients who don't present a protective level of anti-HBs (<10.0 mIU/ml). METHODS Consecutive patients from surgical/...

A 60-year-old woman with end stage liver cirrhosis caused by genotype 2 hepatitis C virus (HCV) infection received an orthotopic liver transplantation (OLT). The patient was negative for the hepatitis B surface antigen (HBsAg) and positive for the anti-hepatitis B surface antibody (anti-HBs) prior to and one and a half months following the OLT. Due to reactivation of hepatitis C, treatment with...

Background: Following WHO recommendation, HBV vaccination has been integrated into EPI program in Iran since 1996. Objective: To evaluate the immunogenicity and protective effect of HB vaccine (recombinant Heberbiovac ,Cuba ) in vaccinated children and adults . Methods: A total of 542 cases (340 children and 202 adults) were vaccinated using a three-doses schedule of zero, one and six month. Bl...