Abstract Haplophyllum tuberculatum is a plant commonly used in folk medicine to treat several diseases including vomiting, nausea, infections, rheumatism, and gastric pains. In the current study, H. essential oils, hydrosols, pure compounds R-(+)-limonene, S-(−)-limonene, 1-octanol, as well their combinations R-(+)-limonene/1-octanol S-(−)-limonene/1-octanol, were screened for cytotoxicity on H...

Natural products are known to be a continuous source of potential anti-cancer agents due their chemical and biological diversity. This study aimed evaluate the in vitro cytotoxic properties medicinal plants mechanisms action human malignant melanoma cells. The investigated effect extracts on cell cycle, caspase-3/7, apoptosis induction using Annexin V-FITC/PI staining, morphological changes lac...

BACKGROUND Plants used for traditional medicine produce diverse and complex secondary metabolites exhibiting various medicinal properties. The medicinal plant Haplophyllum tuberculatum is used by native people against malaria and parasitic infections. METHODS In this study and in order to contribute for the search of new natural drugs for leishmaniasis, the essential oils of H. tuberculatum l...

Abstraet-l . The effects of the amino acid, aspartate, as an allosteric modifier of pyruvate kinase (PK) were surveyed in tissue extracts from 18 species of animals. 2. Aspartate was a strong activator of PK in selected tissues of gastropod and bivalves molluscs, particularly amongst anoxia-tolerant species; with one exception, a polychaete worm, aspartate had no effect on PK from non-molluscan...

The experiment was carried out to investigate the effects of Alisma canaliculatum with probiotics (ACP) on the growth performance, meat composition, oxidative stability, and fatty acid composition of broiler meat. Sixteen probiotic strains were tested for their levels of acid, bile, and heat tolerance. Among them, Lactobacillus acidophilus KCTC 3111, Enterococcus faecium KCTC 2022, Bacillus sub...