abstract: griscelli syndrome (gs) is a rare disease first described in 1978. it is inherited in autosomal recessive pattern. this disease is characterized by partial albinism, pigmentation dilution, cellular immunodeficiency, neurological involvement & uncontrolled phases of macrophage & lymphocyte activation. we report a 5 months old iranian girl presenting with silver-gray hair,eyelashes and ...

background trichoepithelioma is a rare benign skin lesion that originates from hair follicles. trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. methods we present a large family of iranian origin with 15 individuals affected with multiple familial trichoepithelioma in four generations, and treated with three different methods. results trichoepithelioma is histolog...

Netherton syndrome is a rare autosomal recessive disease characterized by erythroderma, ichthyosis linearis circumflexa, atopy, failure to thrive and a specific hair shaft abnormality called trichorrhexis invaginata or bamboo hair, considered pathognomonic. We report the case of a 4-year-old boy with erythroderma since birth, growth deficit and chronic diarrhea. Trichoscopy was used to visualiz...

A 3.5 month-old girl was admitted with silvery gray hair, light colored skin, recurrent diarrhea, chest infections, hepatosplenomegaly, episodes of pancytopenia, and hemophagocytosis in the bone marrow. Light microscopy of hair showed characteristic large and irregular clumps of melanin in the middle of hair shaft. Peripheral blood smear examination did not show giant granules in granulocytes. ...

Scalp involvement is a prominent and often the initial presentation in patients with psoriasis. Hair growth may be impaired with a hair loss and an increased telogen/anagen ratio. The aim of this study was to investigate the hair density and anagen/telogen ratio in psoriatic patients, using epiluminescence microscopy combined with digital image analysis (TrichoScan). Thirty psoriatic patients w...

Griscelli syndrome is a rare disease characterized by pigment dilution, partial albinism, variable cellular immunodeficiency, and an acute phase of uncontrolled T-lymphocyte, and macrophage activation. Griscelli et al described this syndrome in 1978. Since then, only in approximately 60 cases have been reported, most from the Turkish, and Mediterranean population. In microscopic examination, si...

Androgenetic alopecia is often treated by follicular unit transplantation, a technique that involves minimal risk of hair loss because of the more resistant nature of the donor area. Lichen planopilaris is a cicatricial alopecia that causes permanent destruction of hair follicles. We report two cases of post-transplantation lesions compatible with lichen planopilaris in both recipient and donor...

Arsenic levels were determined in human hair samples collected from a mining and non-mining community in Ghana. Hair samples were digested and analyzed using inductively coupled plasma atomic emission spectrometer (ICP–AES). Elevated levels of arsenic were found in the samples obtained from the mining community, the mean levels in the hair ranged from 0.0142–0.0515 μg/g, whereas arsenic was not...

Observation: Wooly hair is usually present at birth or infancy with a genetic linkage of autosomal dominant or recessive. Hair is curly, thick and often heavily pigmented. This condition has been reported with eye, teeth, cardiac anomalies. Also, keratosis pilaris atrophicans, ichtiyosis and deafness, palmoplantar keratoderma and Noonan syndrome may accompany wooly hair. We report two sisters w...

1 The aim of this study was to objectively assess stress of kangaroos affected by lumpy jaw 2 disease (LJD) using plasma and hair cortisol concentrations. The plasma and hair samples 3 were collected from kangaroos with LJD and healthy controls. Collected hair samples were 4 extracted with methanol after washing with isopropanol, following which they were processed 5 with the cortisol enzyme im...