نتایج جستجو برای: haemophilus influenzae type b hib

تعداد نتایج: 2056403  

2012
Michael L. Jackson Charles E. Rose Amanda Cohn Fatima Coronado Thomas A. Clark Jay D. Wenger Lisa Bulkow Michael G. Bruce Nancy E. Messonnier Thomas W. Hennessy

In response to the 2007-2009 Haemophilus influenzae type b (Hib) vaccine shortage in the United States, we developed a flexible model of Hib transmission and disease for optimizing Hib vaccine programs in diverse populations and situations. The model classifies population members by age, colonization/disease status, and antibody levels, with movement across categories defined by differential eq...

2015
Kusnandi Rusmil Hartono Gunardi Eddy Fadlyana Soedjatmiko Meita Dhamayanti Rini Sekartini Hindra Irawan Satari Nelly Amalia Risan Dwi Prasetio Rodman Tarigan Reni Garheni Mia Milanti Sri Rezeki Hadinegoro Suganda Tanuwidjaja Novilia Sjafri Bachtiar Rini Mulia Sari

BACKGROUND WHO recommended incorporation of Haemophilus influenzae type b (Hib) vaccination into immunization program. Indonesia would adopt Hib as a National Immunization Program in 2013. We aimed at analyzing immunogenicity, safety, and consistency of a new combined DTP-HB-Hib (diphtheria-tetanus-pertussis-Hepatitis B-Haemophilus influenza B) vaccine. METHODS A prospective, randomized, doub...

Journal: :Infection and immunity 2014
Birendra Singh Yu-Ching Su Tamim Al-Jubair Oindrilla Mukherjee Teresia Hallström Matthias Mörgelin Anna M Blom Kristian Riesbeck

Haemophilus influenzae type b (Hib) escapes the host immune system by recruitment of the complement regulator vitronectin, which inhibits the formation of the membrane attack complex (MAC) by inhibiting C5b-C7 complex formation and C9 polymerization. We reported previously that Hib acquires vitronectin at the surface by using Haemophilus surface fibrils (Hsf). Here we studied in detail the inte...

Journal: :Infection and immunity 1997
M H Shearer A H Lucas P W Anderson K D Carey H B Jenson T C Chanh J R Stanley R C Kennedy

These studies were performed to assess the utility of the baboon as a nonhuman primate model to evaluate vaccines for use in humans. Specifically, we examined the antibody response of baboons immunized during the third trimester of pregnancy with Haemophilus influenzae type b (Hib) polyribosylribitol phosphate (PRP) conjugate and unconjugated polysaccharide vaccines. Some of the vaccinated moth...

Journal: :Pediatrics 2012
Elizabeth C Briere Michael Jackson Shetul G Shah Amanda C Cohn Raydel D Anderson Jessica R MacNeil Fatima M Coronado Leonard W Mayer Thomas A Clark Nancy E Messonnier

BACKGROUND Since the introduction of effective vaccines, the incidence of invasive Haemophilus influenzae type b (Hib) disease among children <5 years of age has decreased by 99% in the United States. In response to a limited vaccine supply that began in 2007, Hib booster doses were deferred for 18 months. METHODS We reviewed national passive and active surveillance (demographic and serotype)...

Journal: :Clinical and vaccine immunology : CVI 2013
Timo Vesikari Sven Arne Silfverdal Florence Boisnard Stéphane Thomas Grace Mwawasi Donna Reynolds

This study compared the levels of immunogenicity and safety of diphtheria-tetanus toxoid-five-component acellular pertussis (DTaP(5)), inactivated poliovirus (IPV), and Haemophilus influenzae type b (Hib) (DTaP(5)-IPV-Hib) and DTaP(3)-IPV/Hib vaccines for study participants 3, 5, and 12 months of age. Post-dose 3 noninferiority criteria comparing DTaP(5)-IPV-Hib to DTaP(3)-IPV/Hib using rates o...

Journal: :Pathogens 2023

Background: The evaluation of seroprotection rates against vaccine-preventable infectious diseases allows for the identification risk populations. HIV-exposed infants, even if not infected with HIV, have higher morbidity and mortality in comparison to unexposed counterparts. aim this study was compare specific IgG levels Haemophilus influenzae type-B (HiB), Hepatitis-B (HBV), Streptococcus pneu...

2012
Kristina A. Bryant Jodie McVernon Colin D. Marchant Terry Nolan Gary S. Marshall Peter Richmond Helen Marshall Michael Nissen Stephen B. Lambert Emmanuel Aris Narcisa Mesaros Jacqueline M. Miller

A pooled analysis was conducted of 1257 toddlers who received a fourth dose of Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine (HibMenCY-TT) or Hib conjugate vaccine (Hib polysaccharide conjugated to N. meningitidis outer membrane protein) coadministered with measles-mumps-rubella (MMR) and varicella (VAR) vaccines (NCT00134719/NCT0028978...

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