نتایج جستجو برای: gw182

تعداد نتایج: 125  

Journal: :The EMBO journal 2009
Xavier C Ding Helge Grosshans

MicroRNAs (miRNAs) repress target genes through a poorly defined antisense mechanism. Cell-free and cell-based assays have supported the idea that miRNAs repress their target mRNAs by blocking initiation of translation, whereas studies in animal models argued against this possibility. We examined endogenous targets of the let-7 miRNA, an important regulator of stem cell fates. We report that le...

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