نتایج جستجو برای: gut

تعداد نتایج: 50393  

2011
Rodrigo Mora Yi-Bin Chen Rune Blomhoff Scott B. Snapper Cathryn Nagler Ramnik J. Xavier Bartira Rossi-Bergmann Jonathan C. Kagan Hans-Christian Reinecker Nir Hacohen C. O. Gomes Deanna D. Nguyen Emiko Mizoguchi Sen Wang Eduardo J. Villablanca Jaime De Calisto Daniel C. O. Gomes

Gut-associated dendritic cells (DC) synthesize all-trans retinoic acid, which is required for inducing gut-tropic lymphocytes. Gut-associated DC from MyD88 2/2 mice, which lack most TLR signals, expressed low levels of retinal dehydrogenases (critical enzymes for all-trans retinoic acid biosynthesis) and were significantly impaired in their ability to induce gut-homing T cells. Pretreatment of ...

Journal: :World Journal Of Advanced Research and Reviews 2023

Background: Autism spectrum disorders (ASD) are complex developmental characterised by several levels of social interaction and communication difficulties. The prevalence children with ASD worldwide is around 1:160, the number cases autism has increased significantly. oral microbiome a diverse microbial biofilm second most microbiota in human body after gut. Several factors, such as lifestyle h...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Sophie Leclercq Sébastien Matamoros Patrice D Cani Audrey M Neyrinck François Jamar Peter Stärkel Karen Windey Valentina Tremaroli Fredrik Bäckhed Kristin Verbeke Philippe de Timary Nathalie M Delzenne

Alcohol dependence has traditionally been considered a brain disorder. Alteration in the composition of the gut microbiota has recently been shown to be present in psychiatric disorders, which suggests the possibility of gut-to-brain interactions in the development of alcohol dependence. The aim of the present study was to explore whether changes in gut permeability are linked to gut-microbiota...

Journal: :Alcohol and alcoholism 2017
Jamie E Temko Sofia Bouhlal Mehdi Farokhnia Mary R Lee John F Cryan Lorenzo Leggio

Aims Accumulating evidence for the influence of the gut microbiota on the bidirectional communication along the gut-brain axis suggests a role of the gut microbiota in eating disorders (EDs) and alcohol and substance use disorders. The potential influence of altered gut microbiota (dysbiosis) on behaviors associated with such disorders may have implications for developing therapeutic interventi...

2018
Ryu Okumura Kiyoshi Takeda

Background The intestine is inhabited by a tremendous number of microorganisms, which provide many benefits to nutrition, metabolism and immunity. Mucosal barriers by intestinal epithelial cells make it possible to maintain the symbiotic relationship between the gut microbiota and the host by separating them. Recent evidence indicates that mucosal barrier dysfunction contributes to the developm...

Journal: :PLoS ONE 2008
Rongqian Wu Weifeng Dong Youxin Ji Mian Zhou Corrado P. Marini Thanjavur S. Ravikumar Ping Wang

BACKGROUND Gut ischemia/reperfusion (I/R) injury is a serious condition in intensive care patients. Activation of immune cells adjacent to the huge endothelial cell surface area of the intestinal microvasculature produces initially local and then systemic inflammatory responses. Stimulation of the vagus nerve can rapidly attenuate systemic inflammatory responses through inhibiting the activatio...

Journal: :The Journal of experimental biology 2012
Lisa Robertson E Patricia Rodriguez Angela B Lange

The regulation of insect gut physiology is complex and involves the interactions of a number of mechanisms, including the neural regulation of gut contraction by altering neural input and the modulation of gut contractions by neuropeptides directly affecting the muscle. The FGLa-type allatostatins (FGLa/ASTs) are known brain/gut peptides with numerous physiological roles, including modulation o...

2018
Helen T. Groves Leah Cuthbertson Phillip James Miriam F. Moffatt Michael J. Cox John S. Tregoning

Alterations in the composition of the gut microbiota have profound effects on human health. Consequently, there is great interest in identifying, characterizing, and understanding factors that initiate these changes. Despite their high prevalence, studies have only recently begun to investigate how viral lung infections have an impact on the gut microbiota. There is also considerable interest i...

2017
Takehiro Kamo Hiroshi Akazawa Wataru Suda Akiko Saga-Kamo Yu Shimizu Hiroki Yagi Qing Liu Seitaro Nomura Atsuhiko T Naito Norifumi Takeda Mutsuo Harada Haruhiro Toko Hidetoshi Kumagai Yuichi Ikeda Eiki Takimoto Jun-Ichi Suzuki Kenya Honda Hidetoshi Morita Masahira Hattori Issei Komuro

Emerging evidence has suggested a potential impact of gut microbiota on the pathophysiology of heart failure (HF). However, it is still unknown whether HF is associated with dysbiosis in gut microbiota. We investigated the composition of gut microbiota in patients with HF to elucidate whether gut microbial dysbiosis is associated with HF. We performed 16S ribosomal RNA gene sequencing of fecal ...

2016
Bernardino Oliva Sebastià March Cristina Gadea Erik Stolper Magdalena Esteva

OBJECTIVES The gut feelings of doctors can act as triggers and modulators of the diagnostic process. This study explored the existence, significance, determinants and triggers of gut feelings among Spanish general practitioners. DESIGN Qualitative study using focus groups. Thematic content analysis. SETTING Primary healthcare centres in Majorca (Spain). PARTICIPANTS 20 purposively sampled...

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