Guselkumab (GUS) studies in plaque psoriasis (PsO) have established a favorable safety profile for the drug. To evaluate cumulative experience PsO, we pooled placebo-controlled (wk 0-16 CNTO1959PSO2001, CNTO1959PSO3001/3002, and CNTO1959PSO3006) end-of-reporting 0-40 CNTO1959PSO3006; wk16-44 CNTO1959PSO3003; wk0-52 CNTO1959PSO2001 CNTO1959PSO3004; wk0-56 CNTO1959PSO3009; through wk264 CNTO1959P...

a stable agrobacterium-mediated transformation system was established using bialaphos as the selective agent in soybeans [glycine max (l.) merr.]. the cotyledonary node explants of the soybean cultivar ‘ny-1001’ were inoculated with the agrobacterium tumefaciens strain eha105, harboring the vector pcambia3301 containing the gus gene as the reporter gene and the bar gene conferring bialaphos res...

IMAGES ‘ictal 2008 02’ ‘ictal 2008 06’ 50 [7_TD$DIFF] [8_TD$DIFF] 75cm C-type prints, 2008 ‘Post [10_TD$DIFF]ictal’ 30[11_TD$DIFF] cm 30 cm C-type print, 2008 [13_TD$DIFF] ‘Corridor’ [14_TD$DIFF] 38 cm [16_TD$DIFF] 32 cm digital print, 2009 Several years ago I began assessment for possible surgery. This startedwith video telemetry and I was able towatchmyself having seizures after 15 years of n...

One of the major features of P-glucuronidase (GUS) expression in inbred strains of the house mouse, Mus musculus, is the responsiveness of this enzyme to androgen stimulation in tubule cells of the kidney. Both GUS-specific and nonspecific mutations have been described which define genes that serve to control this response. During examination of the expression of GUS in the interbreeding subspe...

Cytokinins play an important role in vascular development. But knowledge on the cellular localization of this growth hormone in the stem and other organs of woody plants is lacking. The main focus of this study was to investigate the occurrence and cellular localization of active cytokinins in leaves, roots, and along the stem of Populus × canescens and to find out how the pattern is changed be...

Tobacco plants were transformed with constructs in which the transgene was a cDNA of replicating potato virus X (PVX) RNA. The constructs, referred to here as amplicons, were the intact genome of PVX and PVX constructs modified to carry the beta-glucuronidase (GUS) reporter gene either as an additional gene or as a replacement for the coat protein gene (PVX/GUS/CP and PVX/GUS respectively). Tra...

The expression patterns of senescence-related genes were determined during ozone (O(3)) exposure in Arabidopsis. Rosettes were treated with 0.15 microL L(-1) O(3) for 6 h d(-1) for 14 d. O(3)-treated leaves began to yellow after 10 d of exposure, whereas yellowing was not apparent in control leaves until d 14. Transcript levels for eight of 12 senescence related genes characterized showed induc...

Agrobacterium tumefaciens is established as a vector for gene transfer in many dicotyledonous plants but is not accepted as a vector in monocotyledonous plants, especially in the important Gramineae. The use of Agrobacterium to transfer genes into monocot species could simplify the transformation and improvement of important crop plants. In this report we describe the use of Agrobacterium to tr...