Background Effective interventions on exclusive breastfeeding that are appropriate for the existing conditions can have significant benefits on maintenance, continuity, and promotion of breastfeeding in mothers. The aim of this study is to evaluate the effect of Fenugreek on breast milk sufficiency in nursing mothers. Materials and Methods<...

Vandetanib (ZD6474) is an oral small molecule inhibitor of multiple intracellular receptor kinases, including the vascular endothelial growth factor receptor (VEGFR) -2 and epidermal growth factor receptor (EGFR). Both VEGFR and EGFR pathways have emerged as instrumental in the growth and metastasis of multiple malignancies, including non-small cell lung cancer (NSCLC). Indeed, inhibitors of ea...

We perturbed the growth rate estimates for the resistant mutants by the multiplicative random factor (1 + 0.2 · U [−1, 1]) representing a 20% noise level, and performed 100 randomized trials. Table S1 shows the probability of sensitivity to imatinib (I), dasatinib (D), imatinib + dasatinib (I+D), and imatinib + dasatinib + nilotinib (I+D+N) for the baseline unperturbed growth rates, as well as ...

Contemporary advancements have had little impact on the treatment of gastric cancer (GC), the world's second highest cause of cancer death. Agents targeting human epidermal growth factor receptor mediated pathways have been a common topic of contemporary cancer research, including monoclonal antibodies (mAbs) and receptor tyrosine kinase inhibitors (TKIs). Trastuzumab is the first target agent ...

Introduction: Diarrheal diseases are a serious health problem and important causes of growth retardation and death in the developing world, especially those of prolonged duration. Since diarrhea is constantly found in children with zinc deficiency, very studies supported zinc supplements beneficial on the duration and severity of diarrhea among children. We review the impact of zinc effects on ...

Objective To characterize cancer clinical trials in Latin America and the Caribbean (LAC), with a focus on registration and enrollment trends. Methods Data were collected from 1 285 active cancer clinical trials registered up until 31 May 2014 in the World Health Organization's International Clinical Trial Registry Platform (ICTRP). The trials were categorized by six characteristics of the cont...

The potential of pine resin as a renewable non-timber product is furthering the socioeconomic relevance industry in Europe, where maritime (Pinus pinaster Ait.) main tapped species. Characterizing genetic resources terms yield and its covariation with tree growth crucial to implement efficient breeding programs aiming maximize without negatively impact growth. We explored variation among proven...

little scientific information is available that has evaluated safflower (carthamus tinctorius) cake as a substitute to conventional ingredients in small ruminants diet. the objective of this work was to evaluate the effect of feeding safflower cake in total mixed rations (tmrs) on lamb and kid growth rates, carcass traits and meat fatty acid composition. two consecutive trials were conducted us...

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