ôbjective: the mood disorder questionnaire (mdq) has been designed as a screening self-report inventory for diagnosing bipolar mood disorders. this study investigated the validity and the optimal cut-off threshold of the persian version of mdq in a group of ïranian depressive patients. methods: ône hundred and twenty patients with probable diagnosis of mood disorders attending psychiatric clini...

BACKGROUND Major depression has been associated with endocrine and immune alterations, in particular a dysregulation of the hypothalamus-pituitary-adrenal system with subsequent hypercortisolism and an imbalance of pro- and anti-inflammatory cytokines. Recent studies suggest that vascular endothelial growth factor (VEGF), a cytokine involved in angiogenesis and neurogenesis, may also be dysregu...

Introduction: methylmalonic acidemia (MMA) is a metabolic disorder and especial nutritional support has an important role in improvement of growth and development in these patients. Case presentation: A 3-month old female infant with known MMA was admitted to emergency department of Dr Sheikh Children Hospital with primary diagnosis of pneumonia and sepsis .This patient was a full term baby; MM...

  Background : Malnutrition is still a major health problem in the developing countries. It is recognized that 60% of deaths among children under five year in these countries are associated with malnutrition. The aim of this study was to estimate the prevalence of malnutrition in children under 5 years old in Iranshahr in 2011.   Materials and Methods : This is a cross-sectional de...

Down syndrome (DS) is a chromosomal disorder associated with short stature and psychomotor delay. Growth hormone (GH) and insulin-like growth factor I (IGF-I) are of interest in DS as the pronounced growth retardation coincides in time when GH becomes essential for growth. Simultaneously mean intelligence quotient (IQ) decreases

abstract background and aim: the intolerance of uncertainty model was initially developed as an explanation for worry within the context of generalized anxiety disorder. however, recent research has identified intolerance of uncertainty (iu) as a transdiagnostic maintaining factor across the anxiety disorders. the aim of the present study was to compare the intolerance of uncertainty in patient...

CONTEXT Preterm birth, intrauterine growth restriction, and delivery-related hypoxia have been associated with schizophrenia. It is unclear whether these associations pertain to other adult-onset psychiatric disorders and whether these perinatal events are independent. OBJECTIVE To investigate the relationships among gestational age, nonoptimal fetal growth, Apgar score, and various psychiatr...

To the Editor: Aripiprazole, a D2 partial agonist antipsychotic, was recently approved by the US Food and Drug Administration for major depressive disorder (MDD) add-on therapy. Its effects are believed to be related to its 5-HT1A partial agonist, 5-HT2C antagonist, and 5-HT2A antagonist properties. Here, I present a case of MDD with panic disorder in which improvement of symptoms was seen afte...

objective: to report the case of a 46-year old male with major depressive disorder, who represented manic symptoms, when olanzapine was added to his treatment. method: a 46-year old female, with a diagnosis of treatment resistant depression was referred to the authors. he had past history of depression for more than 20 years. the symptoms were present nearly every day since 1981, without any di...